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- 4Agricultural, Food and Nutritional Science, Department of
- 4Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
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- 4Graduate Studies and Research, Faculty of/Theses and Dissertations
- 2Roy Berg Kinsella Research Ranch
- 2Roy Berg Kinsella Research Ranch/Journal Articles (Kinsella Ranch)
Differences in whole blood gene expression associated with infection time-course and extent of fetal mortality in a reproductive model of type 2 porcine reproductive and respiratory syndrome virus (PRRSV) infectionDownload
Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) infection of pregnant females causes fetal death and increased piglet mortality, but there is substantial variation in the extent of reproductive pathology between individual dams. This study used RNA-sequencing to characterize the whole...
Intravaginal lactic acid bacteria modulated local and systemic immune responses and lowered the incidence of uterine infections in periparturient dairy cowsDownload
The objective of this investigation was to evaluate whether intravaginal infusion of a lactic acid bacteria (LAB) cocktail around parturition could influence the immune response, incidence rate of uterine infections, and the overall health status of periparturient dairy cows. One hundred pregnant...
Human T-lymphotropic virus type I (HTLV-I) is a persistent human retrovirus characterized by life-long infection and risk of developing HAM/TSP, a progressive neurological and inflammatory disease. Despite extensive studies of HTLV-I, a complete understanding of the viral dynamics has been...
Neonates with intestinal failure (IF), who must rely on parenteral nutrition (PN) for growth and maintenance of health, are at risk for intestinal failure-associated liver disease (IFALD). In neonates, short bowel syndrome (SBS) as a result of intestinal resection is the most common cause of IF....
Novel Mucosal Vaccines to Improve Immune and Health Status of Periparturient Dairy Cows and Increase their Productive PotentialsDownload
The transition period is critical for the health and productivity of dairy cows. Feeding high-grain diets immediately after parturition is necessary to support high milk production. However, high-grain diets are associated with acidic rumen pH and alterations in the composition of rumen...
Potential regulatory role of microRNAs in the development of bovine gastrointestinal tract during early lifeDownload
This study aimed to investigate the potential regulatory role of miRNAs in the development of gastrointestinal tract (GIT) during the early life of dairy calves. Rumen and small intestinal (mid-jejunum and ileum) tissue samples were collected from newborn (30 min after birth; n = 3), 7-day-old...
Repeated oronasal exposure to lipopolysaccharide induced mucosal IgA responses in periparturient dairy cowsDownload
This study investigated the effects of repeated oronasal treatment with lipopolysaccharide (LPS) on the humoral immune responses in saliva, vaginal mucus, and the plasma markers of the acute phase response in periparturient dairy cows. One hundred pregnant Holstein cows were administered either 3...
Gene duplication is a widespread phenomenon in genome evolution, and it has been proposed to serve as an engine of evolutionary innovation. In the present study, we performed the first comprehensive analysis of duplicate genes in the bovine genome. A total of 3131 putative duplicated gene pairs...
Short-chain fatty acids influence host immunity, mucus secretion and microbial community structure to reduce enteritisDownload
Optimal intestinal health is critical to overall host well-being, and acute and chronic enteric inflammatory diseases impart a significant detrimental impact on Canadians. The consumption of dietary fibre (DF) has long been associated with providing a health benefit to individuals, and regulatory...
The endosymbiont Wolbachia pipientis induces the expression of host antioxidant proteins in an Aedes albopictus cell lineDownload
Wolbachia are obligate intracellular bacteria which commonly infect arthropods. They are maternally inherited and capable of altering host development, sex determination, and reproduction. Reproductive manipulations include feminization, male-killing, parthenogenesis, and cytoplasmic...