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- 3Chakrabarti, Subhadeep
- 3Proctor, Spencer D.
- 3Steele, Michael A.
- 3Wu, Jianping
- 2AlZahal, Ousama
- 72Graduate and Postdoctoral Studies (GPS), Faculty of
- 72Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 24Agricultural, Food and Nutritional Science, Department of
- 24Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 5Nursing, Faculty of
- 5Nursing, Faculty of/Health Equity
- 18Department of Agricultural, Food, and Nutritional Science
- 5Department of Medicine
- 5Faculty of Pharmacy and Pharmaceutical Sciences
- 5Medical Sciences-Paediatrics
- 4Centre for Neuroscience
- 4Department of Physiology
- 2Bell, Rhonda (Agricultural, Food, and Nutritional Science)
- 2Jamali, Fakhreddin (Faculty of Pharmacy and Pharmaceutical Sciences)
- 2Kerr, Bradley (Anesthesiology and Pain Medicine)
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The endosymbiont Wolbachia pipientis induces the expression of host antioxidant proteins in an Aedes albopictus cell line
Download2008
Harris, H.L., Brennan, L.J., Keddie, B.A., Braig, H.R.
Wolbachia are obligate intracellular bacteria which commonly infect arthropods. They are maternally inherited and capable of altering host development, sex determination, and reproduction. Reproductive manipulations include feminization, male-killing, parthenogenesis, and cytoplasmic...
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Spring 2014
Bleeding during pregnancy affects as many as one in four pregnancies with roughly half of these resulting in pregnancy loss. An interpretive descriptive design was employed to explore the research question: “How do women with bleeding in early pregnancy describe their experience of waiting in the...
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Spring 2011
Human Cytomegalovirus (HCMV) is the most common cause of congenital infection in newborns. One mechanism for this virus to reach the fetus is to cross the placenta through the syncytiotrophoblast layer. Accumulation and protection of pathogens in the syncytiotrophoblast could affect the systemic...
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The prognosis and outcomes of patients with a ST-segment elevation myocardial infarction and the biochemical and clinical inflammatory response
DownloadSpring 2013
Acute myocardial infarction, and specifically coronary plaque rupture, has been associated with a systemic inflammatory cascade. Using multiple large clinical trial datasets, we sought to further understand the systemic and clinical inflammatory responses in patients with ST-elevation myocardial...
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Spring 2017
MS is a chronic demyelinating disease of the CNS that presents with debilitating symptoms in the later stages of disease progression and therefore a high demand for targeted disease-modifying treatments exists. In order to create effective treatments the causalities between the symptoms and...
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Fall 2017
The inflammatory response is a complex biological process initiated following the recognition of noxious stimuli. It is composed of an elaborate cascade of both pro- and anti-inflammatory mediators, essential for effective defenses against infection, the removal of damaged cells, and the...
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Spring 2015
The tumor suppressor protein Ras association domain family 1A (RASSF1A) has roles in multiple signaling pathways including modulating apoptosis, the cell cycle, DNA damage, and microtubule organization. RASSF1A has been shown to be one of the most frequently epigenetically silenced genes in a...
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Transcriptomic and epigenetic profiling of the lung of influenza-infected pigs: A comparison of different birth weight and Susceptibility groups
Download2015-09-22
Harding, John C.S., Foxcroft, George R., Gunvaldsen, Rayna E., Dyck, Michael K., Plastow, Graham S., Detmer, Susan E., Wilkinson, Jamie M., Dixon, Walter T.
Influenza viruses are a common cause of respiratory disease in swine. Infections range in severity from asymptomatic to causing significant morbidity. The main objective of this study was to compare lung transcriptomic and epigenetic responses to influenza infection in pigs from high or low birth...
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Understanding postprandial inflammation and its relationship to lifestyle behaviour and metabolic diseases
Download2012
Cabezas, Manuel C., Mamo, John C., Proctor, Spencer D., Botham, Kathleen M., Klop, Boudewijn
Postprandial hyperlipidemia with accumulation of remnant lipoproteins is a common metabolic disturbance associated with atherosclerosis and vascular dysfunction, particularly during chronic disease states such as obesity, the metabolic syndrome and, diabetes. Remnant lipoproteins become attached...