Search

Fall 2009

Clark, Darren

Stroke is a leading cause of disability in Canada. Delayed hypothermia improves outcome in patients following cardiac arrest and reduces lesion volume in rodents after transient focal ischemia, but less is known about the effectiveness of delayed hypothermia following permanent focal ischemia. In...

2011

Birch DW, Manouchehri N, Shi X, Hadi G, Karmali S

Fall 2016

Przyslupski, Ann-Marie T

Hypoxic-ischemic brain damage (HIBD) is still of major concern in the neonatal period, resulting in chronic neurological sequelae stemming from damage to the term newborn brain. Full-body and focal-head cooling within 6 hours of birth have proven neuroprotective in human newborns and various...

Fall 2011

Silasi, Gergely

Blood flow to the brain may be disrupted by either a stroke (such as focal ischemia or hemorrhage) or cardiac arrest, where the whole brain becomes ischemic. Both forms of injury result in irreversible neuronal loss leading to neurological impairments and a decrease in the quality of life....

2010

Vohra S, Alderdice F, Jenkins JG, McCall EM, Halliday HL

Spring 2016

Klahr, Ana C

Mild therapeutic hypothermia (HYPO), decreasing brain temperature to 32-35°C, is the gold standard neuroprotectant against ischemia. Cooling also ameliorates several cell death mechanisms in other types of brain injury (e.g., traumatic brain injury). As with many other neuroprotectants, HYPO not...