This decommissioned ERA site remains active temporarily to support our final migration steps to https://ualberta.scholaris.ca, ERA's new home. All new collections and items, including Spring 2025 theses, are at that site. For assistance, please contact erahelp@ualberta.ca.
Search
Skip to Search Results-
Effect of Adenovirus-mediated Decorin Gene Therapy on Fibrotic Remodeling in Tissue-engineered Skin
DownloadFall 2016
Background: Hypertrophic scar (HTS) is a fibroproliferative disorder of the skin that results in the development of painful, red, raised scar lesions. Transforming growth factor beta 1 (TGF-β1) has been implicated as a key driver of this disorder. Primarily, these effects include an increased...
-
Fall 2016
Hypertrophic scars (HTS) are caused by trauma or burn injuries to the deep dermis and can cause cosmetic disfigurement and psychological issues. Our lab has established a human HTS-like nude mouse model, in which the grafted human skin develops red, raised, and firm scarring, resembling...
-
Fall 2019
Background: Dermal fibroproliferative disorders are forms of aberrant cutaneous wound healing, which can lead to the formation of hypertrophic scars (HTS). HTS develop after prolonged healing of deep dermal burns and are associated with excessive inflammation. HTS are characterized by exaggerated...
-
The Role of Decorin and Factors Influencing its Expression in Wound Healing and Hypertrophic Scarring
DownloadSpring 2016
Hypertrophic scarring following deep burn injury is a significant problem for many burn patients, and can cause lifelong morbidity including impaired physical function, and reduced psychosocial function from poor cosmesis. While a significant body of research exists, there is still no gold...