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B cell Tolerance Mechanisms Following ABO-incompatible Infant Heart Transplant: A Potential Role for CD22
DownloadSpring 2015
Due to presumed immune immaturity, infants are able to accept heart transplants across the ABO barrier, a procedure that would result in catastrophic consequences if performed in adults. Our group has demonstrated that following ABO-incompatible heart transplantation (ABOi HTx), infants develop...
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Hypothermic and Subnormothermic Ex-situ Heart Perfusion: Examining Diverse Strategies and Their Effects on Heart Function Preservation
DownloadFall 2024
Mainardi Aguiar da Silva, Guilherme
The number of people suffering from heart failure grows annually. For those people who have advanced heart failure and are eligible for a heart transplant, this is the gold standard procedure to treat them. Allowing not only an improvement in quality of life but also an increase in...
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Spring 2022
The overall goal of this study is to improve the protocols for Ex Situ heart perfusion (ESHP) to better preserve the function and viability of donated hearts. ESHP has emerged as a new method of donor heart preservation. Unlike the standard cold storage technique, in ESHP, the heart is perfused...