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- 1Beaudoin, Frédéric
- 1Bernal, María Margarita
- 1Goldansaz, Seyed Ali
- 1Guan, Leluo
- 1Ibeagha-Awemu, Eveline M.
- 1Jin, Weiwu
Shiga toxin producing Escherichia coli (STEC) strains are pathogens which frequently cause human intestinal diseases. The main virulence factor Shiga toxin (Stx) is encoded by the gene located on the Stx prophage and gene expression is affected by the diversity of Stx prophage genome. Nineteen...
Evaluating the Role of Bacterial Lipopolysaccharide on Etiology and Pathogenesis of Transmissible Spongiform EncephalopathiesDownload
Transmissible spongiform encephalopathies (TSEs) or otherwise known as prion diseases are a class of fatal neurodegenerative diseases related to irreversible brain damage. Presently, there is no effective treatment or preventive strategy for this disease because the etiology and biological...
Salmonella survives in low moisture products over an extended time. Salmonella also resists dry heat, which questions the assumption that Salmonella outbreaks from intermediate moisture foods result mostly from post-processing contamination. Some Enterobacteriaceae possess a genomic island called...
Bacteria need to adapt to the ever-changing conditions in the environment and Escherichia coli employs the Cpx two-component system to protect the envelope, which consists of the inner membrane, periplasm, peptidoglycan, and outer membrane. Cpx is known to sense and respond to protein misfolding...
The Spatiotemporal Occurrence and Recovery of Shiga Toxin-producing Escherichia coli (STEC) in Well-sourced Drinking Water from Southern Alberta, CanadaDownload
Shiga toxin-producing Escherichia coli (STEC) are important enteric pathogens that cause significant morbidity and mortality worldwide, as well as in Canada. Drinking water is a key exposure pathway for STEC infection and the occurrence of these pathogens in drinking water sources represents an...
Transcriptome microRNA profiling of bovine mammary epithelial cells challenged with Escherichia coli or Staphylococcus aureus bacteria reveals pathogen directed microRNA expression profilesDownload
Background MicroRNAs (miRNAs) can post-transcriptionally regulate gene expression and have been shown to be critical regulators to the fine-tuning of epithelial immune responses. However, the role of miRNAs in bovine responses to E. coli and S. aureus, two mastitis causing pathogens, is not well...