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Skip to Search Results- 1Alanis, Ramon
- 1Alford, Spencer Caleb
- 1Anbukarasu, Preetam
- 1Assempour, Nazanin
- 1Belal, Ahmed S. F.
- 1Boulet, Joel L
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Development of a Multisectorial Electroactive Nanowell Platform for Selective Single-Cell Sorting and Quantification
DownloadSpring 2022
The rapid isolation of specific rare target cells is of rising importance in current targeted patient treatment plans. Common cell sorting approaches such as stream-based dielectrophoresis (DEP) based cell sorters are limited by their spatial dimensions as only a number of cell types...
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Development of an optical biosensor based on Mach-Zehnder Interferometry for detection of Listeria monocytogenes
DownloadFall 2013
Label-free optical biosensors are widely used for the detection of pathogens due to their low-cost, real-time detection and high sensitivity. A Mach-Zehnder Interferometer (MZI) based biosensor has been developed for the detection of gram-positive bacteria, Listeria monocytogenes. An extensive...
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Spring 2013
The discovery of green fluorescent protein (GFP) from the Aequorea victoria jellyfish revolutionized many fields in the scientific community, including molecular biology, protein engineering, and neuroscience. The ability to genetically link a fluorescent protein to a protein of interest has...
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Fall 2012
Fluorescent proteins (FPs) are indispensible biochemical tools. The concerted efforts of protein engineers have produced FPs spanning the visible colour spectrum. This wide variety of FPs has greatly facilitated the development of FP-based biosensors. However, researchers rely on relatively few...
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Fall 2013
The discovery of green fluorescent protein (GFP) from the Aequorea victoria Jellyfish followed by the extensive efforts of protein engineers to produce other fluorescent proteins (FPs) spanning the visible color spectrum made fluorescent proteins indispensable biochemical tools in the scientific...
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Fall 2014
The discovery and subsequent applications of fluorescent proteins (FPs) launched a new era for live cell fluorescence imaging. The design and developments of FP-based indicators have further solidified the versatility of FPs and rendered them as indispensable tools in life science research now...
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Fall 2011
AC Dielectrophoresis, the motion of dielectric colloidal particles in the presence of an inhomogeneous AC electric field, has been utilized in this work as a mechanism for preventing channel wall fouling due to particle deposition for a multi-component colloidal system. Both attractive and...
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Spring 2013
The sources of inducing field gradients and their implications are investigated inside the microfabricated post arrays. A parametric study is conducted to understand how the posts arrangements, distance, and size change the field and field gradients. The results provide criteria where the...
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Fall 2012
We present three articles written to satisfy the requirements for the Ph.D. degree in Operations and Information Systems: The first is focused on the use of a bidimensional Markov model to compute the expected performance of an ambulance system using dynamic ambulance repositioning based on the...
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Spring 2015
Fluorescent proteins (FP) and FP-based biosensors have become essential tools for cell biology and neuroscience research. This thesis describes efforts to engineer new FPs with red emission and novel genetically encoded biosensors based on red FPs. Directed evolution and semi-rational design are...