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Gluten-sensitive enteropathy, called Celiac disease (CD), is one of the most frequent autoimmune diseases, occurring in 1% people worldwide, upon gliadin ingestion. Currently, the only treatment available for CD individual is a strict life-long gluten-free diet. Chicken egg yolk immunoglobulin Y...
Clinical impact of submicroscopic malaria on delivery outcomes and the role of VAR2CSA antibodies in pregnant women from ColombiaDownload
Malaria caused by the genus Plasmodium (P.) is one of the oldest and most important parasitic infections globally. Pregnant women are at an increased risk for malaria, where the disease poses a significant risk to both maternal and child health. Better diagnosis of malaria can have an immediate...
The In-gel polymerase chain reaction (PCR) technology developed by our group at the University of Alberta makes use of PCR reagents entrapped within nano-liter polyacrylamide gels. To adapt this technology for use at the point of care, methods were developed to preserve gel-based PCR reagents by...
Identification and Exploitation of Oligosaccharyltransferase Dependent Bacterial Glycosylation SystemsDownload
Protein glycosylation, the covalent attachment of carbohydrates to amino acids, was once thought to be a unique attribute of Eukaryotes and select bacteria. However, both N- (attached to asparagine) and O- (attached to serine or threonine) glycosylation systems have been identified in an ever...
In recent decades, condition-based maintenance has been acknowledged as a cost-effective maintenance program and widely used in many engineering systems. Diagnostics and prognostics are critical components of condition-based maintenance, responsible for providing information about present and...
Towards a Better Understanding of Poly(N-isopropylacrylamide) Microgel-Based Etalons and their Continued Development in DiagnosticsDownload
Poly(N-isopropylacrylamide) (pNIPAm) microgel-based etalons are photonic materials that exhibit color based on temperature or other environmental stimuli. These materials provide a new and unique method for biosensing and other applications. Therefore it is important to understand these materials...