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Spring 2017

Kang, Liane J

Introduction: Secretory immunoglobulin A (sIgA) plays a critical role in gut mucosal immunity and is a marker of immune maturation in early life. Delayed IgA production is associated with increased risk of allergic diseases. Animal models of stressful events before birth and during infancy show...

Fall 2024

White, Ryan

This thesis explores how pre-existing mental health factors—anxiety, depression, concussion history, learning disorders, and ADHD—affect post-concussion outcomes in Canadian Football League (CFL) athletes. The study addresses a gap in the literature by investigating whether baseline mental health...

Spring 2018

McKillop, Ashley B

Background: Persistent back pain is a debilitating problem that can threaten many aspects of affected individuals’ lives, including engagement in valued social roles (i.e., participation). Related research often focuses on studying vulnerabilities and deficits, rather than the psychosocial...

2011

Gibson, M., Markle-Reid, M., Thabane, L., Pierce, T., Hoch, J., McAiney, C., Busing, B., Browne, G., Forbes, D.

Background: Very little research has been conducted in the area of depression among older home care clients using personal support services. These older adults are particularly vulnerable to depression because of decreased cognition, comorbid chronic conditions, functional limitations, lack of...

Fall 2019

Aghamohammadi Sereshki, Arash

The world population is dramatically aging. Several factors affect brain in healthy aging. The apolipoprotein E (APOE), brain-derived neurotrophic factor (BDNF) and catechol-O-methyl transferase (COMT) might be involved in neurodegenerative diseases, depression and cognitive decline in healthy...

Fall 2014

Ferdousi, Mehnaz I

Many drugs containing an imidazoline moiety are thought to bind to both imidazoline binding sites (IBS) and α-adrenoceptors (α-AR) to mediate their therapeutic effects. To aid in better characterisation of these binding sites, the structure-affinity relationships of several new series of...

Spring 2024

Singh, Deepak

Mental disorders are one of the leading health problems affecting Canadian children and youth. Teachers are considered frontline workers in child mental health due to the amount of time children spend at school. Given the high prevalence of mental disorders, and the amount of time teachers spend...

2008

Hanson, J., Hayduk, L., Quan, H., Olson, K., Strasser, F., Cui, Y., Lawlor, P., Cree, M.

Background: Symptoms tend to occur in what have been called symptom clusters. Early symptom cluster research was imprecise regarding the causal foundations of the coordinations between specific symptoms, and was silent on whether the relationships between symptoms remained stable over time. This...

Fall 2022

Watt, Makayla Elizabeth

Introduction: Persons with primary biliary cholangitis (PBC) experience significantly higher rates of mental distress, impaired health related quality of life (HrQoL), and fatigue than the general population. While mind-body interventions have been shown to improve mental health and HrQoL, and...

2009

Norris, C., Hegadoren, K.M., da Silva, D.G.V., Lasiuk, G., Chivers-Wilson, K.

Depression is a serious global health problem. It creates a huge economic burden on society and on families and has serious and pervasive health impacts on the individual and their families. Specialized psychiatric services are often scarce and thus the bulk of care delivery for depression has...