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Skip to Search Results- 13Macrophages
- 6Endocytosis
- 6Phagocytosis
- 3Comparative immunology
- 3Dectin-1
- 3Immunoregulatory receptors
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Fall 2013
West Nile virus (WNV) is a neurotropic, blood-borne flavivirus that can cause serious neurological disease in humans and animals. While significant progress has been made in identifying virus-encoded pathogenic determinants, very little is known regarding how these viral proteins interact with...
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Inhalable nanoparticles in lung cancer treatment; efficacy, safety, distribution and nanoparticle-macrophage interactions
DownloadFall 2012
In 2002, lung cancer was responsible for 17.6% of the total worldwide deaths from cancer. Beyond the three traditional forms of cancer treatment, surgery, radiation therapy, and chemotherapy, targeted drug delivery therapy has shown to be a potential treatment option. The design of a successful...
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Fall 2017
The two types of rejection identified in the Banff histopathologic diagnosis are T cell-mediated rejection (TCMR) and antibody-mediated rejection (ABMR). TCMR is most common early post-transplant while ABMR is the main cause of late graft loss. Kidney transplant TCMR is diagnosed histologically...
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Investigating Mechanisms Responsible for the Pro-Regenerative Effects of Conditioning Electrical Stimulation
DownloadFall 2022
Though capable of regeneration, repair surgeries following peripheral nerve injury are often incomplete or entirely unsuccessful. The slow rate of regeneration (1-3mm/day) of a proximal injury requires up to two years to reach the distal target, whereas significant muscle atrophy occurs after...
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Magazine Images Depicting the Ideal Fit Male Body: An Outlet for Influencing Body Perceptions and Exercise Related Cognitions
DownloadFall 2012
This study examined the effects of viewing health/fitness and sports magazine images on body perceptions and exercise related cognitions in males. The moderating effects of age were also examined. A series of 3 (image-only, magazine cover, control) by 3 (youngest, middle, oldest) ANOVA analyses...
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Spring 2020
The human neuraminidases (NEU1, NEU2, NEU3, and NEU4) are a family of enzymes implicated in pathologies including cancer and diabetes. Our group has developed selective inhibitors for these enzymes that have been employed as tools to understand their biological roles. Several reports have linked...
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Molecular Mechanisms of the Activation of the Pattern Recognition Receptor Dectin-1 and its Induction of Immune Responses
DownloadFall 2014
In the past two decades, a rising number of fungi have emerged as serious human pathogens and the incidence of invasive fungal infections has increased enormously. Millions of people contract fungal diseases that kill at least as many people as tuberculosis or malaria, yet the global burden of...