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From G551D to F508del: An Inquiry Into The Development Of Targeted Therapeutics For The Treatment Of Cystic Fibrosis
DownloadFall 2016
Cystic Fibrosis (CF) is a fatal inherited disease caused by mutations in the gene encoding the Cystic Fibrosis Transmembrane Regulator (CFTR) protein. CFTR plays an integral role in salt and water transport across the epithelial membrane of major organs, such as the lungs. CFTR-targeted...
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Lipidomics of Biological Samples for the Assessment of Physiological and Pathological Processes
DownloadFall 2020
Lipids are a large class of hydrophobic molecules involved in energy storage, signaling, modulation of gene expression and membranes. Lipidomics focuses on the comprehensive analysis of lipids and their interactions. Although the potential of lipidomics to study physiological and pathological...