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Skip to Search Results- 2AlZahal, Ousama
- 2Dionissopoulos, Louis
- 2Dunsmore, Garett
- 2Elahi, Shokrollah
- 2McBride, Brian W.
- 2Steele, Michael A.
- 5Agricultural, Food and Nutritional Science, Department of
- 5Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 2Graduate and Postdoctoral Studies (GPS), Faculty of
- 2Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 2WISEST Summer Research Program
- 2WISEST Summer Research Program/WISEST Research Posters
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Adaptation to high grain diets proceeds through minimal immune system stimulation and differences in extracellular matrix protein expression in a model of subacute ruminal acidosis in non-lactating dairy cows
Download2012
AlZahal, Ousama, McBride, Brian W., Dionissopoulos, Louis, Steele, Michael A.
Problem statement: Subacute Ruminal Acidosis (SARA) is a metabolic disorder affecting approximately 20% of all dairy cattle in North America. Although the presence of SARA has been described for some time, the etiology of the disorder remains uncertain. For example, many animals diagnosed with...
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Chronic Fatigue Mechanisms in Autoimmune Diseases: Lessons from Primary Biliary Cholangitis and Systemic Sclerosis
DownloadFall 2023
Systemic sclerosis (SSc) is an autoimmune disease affecting the body's connective tissues, resulting in progressive fibrosis and vasculopathy. In some cases, individuals with SSc may also develop primary biliary cholangitis (PBC), another autoimmune disease characterized by damage to their...
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Spring 2012
Obesity is a major risk factor for the development of type 2 diabetes (T2D). While altered systemic inflammation is associated with the development T2D, the effects of obesity on immune function are not well known. It is not known why some obese individuals develop T2D, and some remain healthy....
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Milk-derived tripeptides IPP (Ile-Pro-Pro) and VPP (Val-Pro-Pro) promote adipocyte differentiation and inhibit inflammation in 3T3-F442A cells
Download2015
Chakrabarti, Subhadeep, Wu, Jianping
Milk derived tripeptides IPP (Ile-Pro-Pro) and VPP (Val-Pro-Pro) have shown promise as anti-hypertensive agents due to their inhibitory effects on angiotensin converting enzyme (ACE). Due to the key inter-related roles of hypertension, chronic inflammation and insulin resistance in the...
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Potential regulatory role of microRNAs in the development of bovine gastrointestinal tract during early life
Download2014
Liang, Guanxiang, Bao, Hua, Guan, Leluo, Griebel, Philip J., Stothard, Paul, McFadden, Thomas B., Malmuthuge, Nilusha
This study aimed to investigate the potential regulatory role of miRNAs in the development of gastrointestinal tract (GIT) during the early life of dairy calves. Rumen and small intestinal (mid-jejunum and ileum) tissue samples were collected from newborn (30 min after birth; n = 3), 7-day-old...
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Small intestine early innate immunity response during intestinal colonization by Escherichia coli depends on its extra-intestinal virulence status
Download2016
Denamur, Erick, Tourret, Jérôme, Dion, Sara, Willing, Benjamin P., Wachtel, Sarah, Finlay, B. Brett, Dufour, Nicolas, Croxen, Matthew A.
Uropathogenic Escherichia coli (UPEC) strains live as commensals in the digestive tract of the host, but they can also initiate urinary tract infections. The aim of this work was to determine how a host detects the presence of a new UPEC strain in the digestive tract. Mice were orally challenged...
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Transcriptomic changes in ruminal tissue induced by the periparturient transition in dairy cows
Download2014
Steele, Michael A., AlZahal, Ousama, Dionissopoulos, Louis, McBride, Brian W., Matthews, James C.
To understand how the capacity for fat metabolism (uptake, synthesis, modification) changes in rumen epithelia immediately before and after onset of lactation in dairy cows, rumen fluid Short Chain Fatty Acid (SCFA) concentrations and mRNA expression profiles of rumen epithelia was determined in...