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- 8Roy Berg Kinsella Research Ranch/Journal Articles (Kinsella Ranch)
- 2Biological Sciences, Department of
- 2Biological Sciences, Department of/Journal Articles (Biological Sciences)
- 1Agricultural, Food and Nutritional Science, Department of
- 1Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
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2010
Clawson,M. L., Wang, Z., Stothard, P., McKay, S., Laegreid, W. W., Williams J. L., Murdoch, B. M., Settles, M., Moore, S. S., Prasad, A.
Background Classical bovine spongiform encephalopathy (BSE) is an acquired prion disease that is invariably fatal in cattle and has been implicated as a significant human health risk. Polymorphisms that alter the prion protein of sheep or humans have been associated with variations in...
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An Assessment of Population Structure in Eight Breeds of Cattle Using a Whole Genome SNP Panel
Download2008
Schnabel, R. D., Wang, Z., Taylor, J. F., Gill, C. A., Van Tassell, C. P., Gao, C., Aerts, J., Williams, J. L., Neto, E. D., Murdoch, B. M., Matukumalli, L. K., Coppieters, W., McKay, S. D., Mannenl, H., Crews, D., Moore, S. S.
Background Analyses of population structure and breed diversity have provided insight into the origin and evolution of cattle. Previously, these studies have used a low density of microsatellite markers, however, with the large number of single nucleotide polymorphism markers that are now...
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Association of a missense mutation in the bovine leptin gene with carcass fat content and leptin mRNA levels
Download2002
Fitzsimmons, C. J., Thue, T. D., Buchanan, F. C., Winkelman-Sim, D. C., Schmutz, S. M., Van Kessel, A. G.
Previously, we have shown that alleles of the BM1500 microsatellite, located 3.6 kb downstream of the leptin gene in cattle, were associated with carcass fat measures in a population of 154 unrelated beef bulls. Subsequently, a cytosine (C) to thymine (T) transition that encoded an amino acid...
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Depauperate genetic variability detected in the American and European bison using genomic techniques
Download2009
Tokarska, M., Demontis, D., Wójcik, J.M., Gregersen, V.R., Loeschcke, V., Pertoldi, C., Coltman, D.
A total of 929 polymorphic SNPs in EB (out of 54, 000 SNPs screened using a BovineSNP50 Illumina Genotyping BeadChip), and 1, 524 and 1, 403 polymorphic SNPs in WB and PB, respectively, were analysed. EB, WB and PB have all undergone recent drastic reductions in population size. Accordingly, they...
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Genome-wide analysis of zygotic linkage disequilibrium and its components in crossbred cattle
Download2012
Jiang, Q., Wang, Z., Yang, R. C., Moore, S. S.
Background Linkage disequilibrium (LD) between genes at linked or independent loci can occur at gametic and zygotic levels known asgametic LD and zygotic LD, respectively. Gametic LD is well known for its roles in fine-scale mapping of quantitative trait loci, genomic selection and evolutionary...
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2008
Kolbehdari, D., Stothard, P., Schnabel, R., Wang, Z., Marques, E., Taylor, J. F., Moore, S. S.
Background Linkage disequilibrium (LD) maps can provide a wealth of information on specific marker-phenotype relationships, especially in areas of the genome where positional candidate genes with similar functions are located. A recently published high resolution radiation hybrid map of bovine...
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2012
Plastow, G., Lu, D., Miller, S., Moore, S., Vander Voort, G., Wang Z., Sargolzaei, M., Li, C., Kelly, M.
Linkage disequilibrium (LD) and the persistence of its phase across populations are important for genomic selection as well as fine scale mapping of quantitative trait loci (QTL). However, knowledge of LD in beef cattle, as well as the persistence of LD phase between crossbreds (C) and purebreds,...
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Spring 2016
Polar bears (Ursus maritimus) were among the first large mammals to be assessed for genetic variation in the wild, and they remain a common subject of genetics studies. Although recent advances in genotyping technology have allowed for more accurate determination of population structure and the...