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Diminishing Returns in Cardiovascular Disease Research: Systematic Review and Meta-analysis
DownloadFall 2019
If “usual care” improves with time, it becomes increasingly difficult for new therapies to demonstrate additional benefit. Our objective then was to determine, by systematic review of randomized trials, whether the absolute cardiovascular risk reduction attributed to community-implemented...
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Does overload exercise training alter autonomic nervous system activity and hemodynamic regulation in aerobically fit men?
DownloadFall 2014
In general, chronic endurance training has positive effects on physiological function. However, the performance of training in excess of what an individual is able to recover from can lead to performance, physiological and psychobiological maladaptation. The purposes of this investigation were to...
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Spring 2016
Both ACE2 and apelin have been reported playing important roles in regulating cardiovascular structure and function. In this study, we used ACE2 or apelin gene knockout or knockdown mice to explore the roles of ACE2 or apelin in cardiovascular diseases. In particular, we created animal disease...
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Fall 2013
Chronic diseases such as diabetes, cardiovascular and renal diseases are major health concerns globally. Cardiovascular diseases with diabetes comprise more than 50% of all deaths attributed to non-communicable diseases worldwide. Acquiring more than one of these diseases at the same time results...