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Skip to Search Results- 1Aldana Hernandez, Paulina
- 1Beggs, Megan R
- 1Berendt, Kimberley D.
- 1Boehme, Cleighton
- 1Briggs, Nicole T
- 1Brophy, Taylor Raymond
- 21Department of Agricultural, Food, and Nutritional Science
- 4Department of Biological Sciences
- 3Department of Medicine
- 3Department of Physiology
- 2Department of Medical Microbiology and Immunology
- 2Faculty of Pharmacy and Pharmaceutical Sciences
- 2Field, Catherine (Agricultural, Food and Nutritional Science)
- 1Alexander, R Todd (Paediatrics)
- 1Baracos, Vickie (Oncology and Agricultural, Food and Nutritional Science)
- 1Bell, Rhonda (Agricultural, Food & Nutritional Science)
- 1Bell, Rhonda (Agricultural, Food and Nutritional Science)
- 1Betti, Mirko (Agricultural, Food and Nutritional Science)
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A Novel Comparative Analysis Approach to Personalize Chemotherapy Dose Calculation in Early Breast Cancer
DownloadFall 2018
Background Worldwide, body surface area [BSA] is used to calculate chemotherapy dose. The BSA formula was originally developed in 1916, derived from height and weight, with no consideration of other patient characteristics. Most chemotherapy agents have a narrow therapeutic index and are...
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Altered ganglioside metabolism in inflammatory bowel disease and the impact of dietary ganglioside intake
DownloadFall 2014
Gangliosides are integral to the structure and function of the plasma membrane. Ganglioside composition of the small intestinal brush border membrane and apical surface of the colon influence numerous cell processes including microbial attachment, cell division, differentiation, and signaling....
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Assessing the Preconception Dietary Intake of Canadian Adults using a new, short dietary assessment tool: The PREP’D Study
DownloadFall 2021
Background: A self-administered, 24-question dietary tool, called the Diet Screening for Adults in Canada (D-SAC), was chosen for use by the Canadian, Healthy Life Trajectories Initiative (HeLTI-Canada). Assessment of the reproducibility and comparability (to another dietary assessment tool) of...
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Spring 2010
Cost-effective processing of dairy whey permeates is important to the environment and economics of the agriculture industry in Canada. Bioconversion of whey permeates is an attractive means of obtaining value-added adjuncts with improved nutritional and functional properties. In the past,...
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Body Composition Assessment in Pediatric Obesity: Reliability, Validity, and Clinical Applications
DownloadFall 2020
Adipose tissue and skeletal muscle have unique metabolic roles. Despite body mass index for age and sex (BMI z-score) being historically widely used to evaluate and monitor health status in children with obesity, it does not depict adiposity and muscularity (or their changes) during growth or...
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Calcium and Vitamin D Intake During Pregnancy and Postpartum in the Alberta Pregnancy Outcomes and Nutrition (APrON) Study
DownloadFall 2016
Calcium and vitamin D are important in maintaining a healthy pregnancy. Low intake/status has been associated with preeclampsia, preterm delivery, lower birth weight, poor fetal skeletal growth, reduced bone mass, and excessive maternal bone loss. Rarely have these nutrients been examined...
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Characterization of the Mitochondrial Phenotype Associated with Primary Biliary Cholangitis
DownloadSpring 2017
Primary Biliary Cholangitis (PBC) is a chronic liver disease characterized by the immune-mediated destruction of intra-hepatic bile ducts. The autoimmune nature of PBC involves humoral and cell-mediated responses that target endogenous mitochondrial proteins. It is thought that the breakdown of...
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Chronic Fatigue Mechanisms in Autoimmune Diseases: Lessons from Primary Biliary Cholangitis and Systemic Sclerosis
DownloadFall 2023
Systemic sclerosis (SSc) is an autoimmune disease affecting the body's connective tissues, resulting in progressive fibrosis and vasculopathy. In some cases, individuals with SSc may also develop primary biliary cholangitis (PBC), another autoimmune disease characterized by damage to their...
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Fall 2019
Indigenous communities in Canada (First Nations, Inuit, and Métis) face significant social and environmental barriers to healthy eating. Due in large part to these barriers, Indigenous children are disproportionally affected by nutrition-related chronic diseases such as obesity and diabetes....