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2013-01-01
Krkošek, M., Ashander, J., Lewis, Mark A., Frazer, N.
The exchange of native pathogens between wild and domesticated animals can lead to novel disease threats to wildlife. However, the dynamics of wild host-parasite systems exposed to a reservoir of domesticated hosts are not well understood. A simple mathematical model reveals that the spill-back...
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An Adminstrative Data Merging Solution For Dealing With Missing Data In A Clinical Registry: Adaptation To ICD-9 to ICD-10
Download2008
Humphries, K., Norris, C.M., Quan, H., Galbraith, P.D., Southern, D.A., Gao, M., Knudtson, M.L., Ghali, W.A., Shrive, F.M.
Background: We have previously described a method for dealing with missing data in a prospective cardiac registry initiative. The method involves merging registry data to corresponding ICD-9-CM administrative data to fill in missing data 'holes'. Here, we describe the process of translating our...
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Documentation of guideline adherence in antenatal records across maternal weight categories: a chart review.
Download2014
Machold, C. A., Kingston, D., McDonald, S. D., Marshall, L.
Background Documentation in medical records fulfills key functions, including management of care, communication, quality assurance and record keeping. We sought to describe: 1) rates of standard prenatal care as documented in medical charts, and given the higher risks with excess weight, whether...
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Identification of a putative quantitative trait nucleotide in guanylate binding protein 5 for host response to PRRS virus infection
Download2015
Choi, I., Guan, L., Plastow, G. S., Liu, P., Koltes, J. E., Loyd, H., Boddicker, N. J., Eisley, C. J., Schroyen, M., Bao, H., Dekkers, J. C. M., Kommadath, A., Abrams, S. M., Reecy, J. M., Rowland, R. R. R., Serão, N. V. L., Lunney, J. K., Carpenter, S., Stothard, P., Fritz-Waters, E., Tuggle, C. K.
Background Previously, we identified a major quantitative trait locus (QTL) for host response to Porcine Respiratory and Reproductive Syndrome virus (PRRSV) infection in high linkage disequilibrium (LD) with SNP rs80800372 on Sus scrofa chromosome 4 (SSC4). Results Within this QTL,...
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Identification of Hepatotropic Viruses from Plasma Using Deep Sequencing : A Next Generation Diagnostic Tool
Download2013-04-17
Jovel, Juan, Wong, Gane K., Mitchell, Troy , Rahbari, Mandana , Zhang, Yong , Mason, Andrew L., Jordan, Tracy, Law, John , Tian, Zhijian , Song, Deyong , O’keefe, Sandra , Carpenter, Eric, Patterson, Jordan , Wang, Weiwei, Meng, Bo , Wasilenko, Shawn T , Ford, Glenn
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Multilocus sequence typing analysis of Clostridium perfringens isolates from necrotic enteritis outbreaks in broiler chickens
Download2008
Jiang, Y. F., Hunter, D. B., Parreira, V. R., Bruce, H. L., Kulkarni, R. R., Prescott, J. F., Chalmers, G., Boerlin, P.
Clostridium perfringens is an important pathogen of animals and humans and is the causative agent of necrotic enteritis (NE) in poultry. This study focuses on the typing of intestinal C. perfringens isolates (n 61) from outbreaks of NE collected from several areas of Southern Ontario, using a...
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Pathologic Evaluation of Type 2 PorcineReproductive and Respiratory SyndromeVirus Infection at the Maternal-FetalInterface of Late Gestation Pregnant Gilts
Download2016-03-10
Novakovic, Predrag, Harding, John C. S., Al-Dissi, Ahmad, Ladinig, Andrea, Detmer, Susan E.
The pathogenesis of fetal death caused by porcine reproductive and respiratory syndromevirus (PRRSV) remains unclear. The objective of this study was to improve our understand-ing of the pathogenesis by assessing potential relationships between specific histopatho-logical lesions and PRRSV RNA...
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2009
Pretorius, V., Majumdar, S.R., McAlister, F.A., Ross, D.B., Norris, C.M., Kapoor, A.S., Mohamed, R.
Background. It has been suggested that the routine use of statins preoperatively would reduce the risk of postoperative infection. We conducted this study to explore whether preoperative statin use was associated with infection after cardiac surgery (recipients of which have a higher-than-average...