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Spring 2015
Biological pathways have the ability to tolerate mutations and evolve to control novel traits. Selection pressures act on these pathways playing a key role in the evolution and divergence of species. Sex determination in Caenorhabditis nematodes is a rapidly evolving trait which can provide...
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Mapping and characterization of mel-43(sb41), a gene required for early embryonic viability in C. elegans
DownloadSpring 2010
A genetic screen for dominant, temperature-sensitive, maternal-effect embryonic lethal mutations identified mel-43(sb41), a gene required for early embryonic viability (Mitenko et al., 1997). Linkage mapping placed mel-43 within a small region on chromosome IV. Genetic analyses suggested that...