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A novel group of zebrafish Class II ADP-ribosylation factors and their potential role in photoreceptor development
DownloadFall 2013
In this study we identified an unknown set of Class II Arf isoforms in zebrafish. Bioinformatics analyses grouped these paralogues into three distinct clades. Using antisense morpholino gene knockdown, we tested the effect of loss of each zebrafish Class II Arf on early development and...
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Characterization of GBF1, Arfs and COPI at the ER-Golgi intermediate compartment and mitotic Golgi clusters
DownloadFall 2009
Protein trafficking between the endoplasmic reticulum (ER) and Golgi complex is regulated by the activity of ADP-ribosylation factors (Arfs). Arf activation by guanine nucleotide exchange factors (GEFs) leads to the recruitment of the coatomer protein COPI and vesicle formation. By using...