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An Exploration of the Associations Between Gut and Serum Immunoglobulin A in Infancy and Asthma in Childhood
DownloadSpring 2020
Introduction Early immune maturation and gut microbial composition have a clear impact on the development of asthma and atopy in children. There is a large body of evidence on the association between immunoglobulin A (IgA), asthma, and other atopic diseases. Low secretory Immunoglobulin A (sIgA)...
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Spring 2014
This thesis examines the pathophysiology of asthma, attempts to determine the cellular mechanisms behind viral-induced immune memory mediated asthma exacerbations, and investigates urinary metabolomic biomarkers of asthma and neonatal hypoxia.