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- 1Carew, Michael W
- 1Donner, Mark
- 1Elshenawy, Osama H. A.
- 1Faucher, Alexandra
- 1Frank, J.
- 1Javed, Muhammad B
- 3Department of Chemistry
- 2Department of Physiology
- 2Department of Renewable Resources
- 2Medical Sciences-Laboratory Medicine and Pathology
- 1Department of Chemical and Materials Engineering
- 1Faculty of Pharmacy and Pharmaceutical Sciences
- 2Leslie, Elaine (Physiology)
- 1Dr. Tariq Siddique (Department of Renewable Resources)
- 1El-Kadi, Ayman (Faculty of Pharmacy and Pharmaceutical Sciences)
- 1Lavasanifar, Afsaneh (Faculty of Pharmacy and Pharmaceutical Sciences)
- 1Le, Chris (Chemistry)
- 1Le, X. Chris (Laboratory Medicine and Pathology)
Arsenic is a widespread environmental contaminant whose toxicity depends on its valence and its chemical form. Arsenic species have been typically determined using high pressure liquid chromatography coupled to inductively coupled plasma mass spectrometry (HPLC-ICPMS), however ICPMS cannot...
An organoarsenic compound, 3-nitro-4-hydroxyphenyl arsenic acid (also known as Roxarsone), has been used as a feed additive. Roxarsone was approved by the Food and Drug Administration (FDA) to control diseases in poultry, and to improve weight gain, feed efficiency, and meat pigmentation....
Hydrotreating is the response to the necessity of a cleaner feed for downstream processes and reduced pollution. Hydrotreating catalysts are vital in this process; hence catalyst deactivation is a key issue. The principal objective of this research was the experimental study of hydrotreating...
Cell-electronic Sensing of Cellular Responses and Toxicity Induced by Nanoparticles and Arsenic SpeciesDownload
We demonstrate the development of a real-time cell analysis (RTCA) platform for studying nanoparticle- and arsenic-induced cytotoxicity with potential applications to risk assessment, environmental toxicity monitoring, and drug development. RTCA is an impedance-based in vitro detection system...
Antimony is naturally occurring in the environment. The assessment of human exposure to environmental antimony is limited. This research focuses on the determination of antimony in water, beverages, and fruit. First, we explored whether there is a correlation between arsenic and antimony in...
Arsenic (As) concentration above the Health Canada and WHO drinking water guidelines of 10 µg L-1 in the Cold Lake area, Alberta is an issue of concern for environmental and human health. The source of groundwater As is ambiguous. This study was initiated to characterize the surficial deposits...
Arsenic is a proven human carcinogen and associated with a myriad of other adverse health effects. This metalloid is methylated in human liver to monomethylarsonic acid (MMAV), monomethylarsonous acid (MMAIII), dimethylarsinic acid (DMAV), and dimethylarsinous acid (DMAIII) and eliminated...
MODULATION OF ARYL HYDROCARBON RECEPTOR (AHR)-REGULATED CARCINOGEN ACTIVATING ENZYMES BY ORGANIC ARSENICALS: A POTENTIAL THERAPEUTIC TARGETDownload
Arsenic is a worldwide environmental pollutant that is associated with skin and several types of internal cancers, such as liver, lung, kidney, urinary bladder, and prostate cancers. Recent reports revealed that organic arsenic metabolites, such as trimethylarsine oxide (TMAO), dimethylarsinic...
This thesis is concerned with NMR studies of solids containing NMR-active quadrupolar nuclei typically overlooked due to their unfavorable NMR properties, particularly moderate to large nuclear electric quadrupole moments. It is shown that <sup>75</sup>As, <sup>87</sup>Sr, and...