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Evaluating the Role of Bacterial Lipopolysaccharide on Etiology and Pathogenesis of Transmissible Spongiform EncephalopathiesDownload
Transmissible spongiform encephalopathies (TSEs) or otherwise known as prion diseases are a class of fatal neurodegenerative diseases related to irreversible brain damage. Presently, there is no effective treatment or preventive strategy for this disease because the etiology and biological...
The majority of triacylglycerol (TG) utilized for very-low density lipoproteins (VLDL) assembly is derived from lipolysis-reesterification of TG stored in lipid droplets (LDs). At least two types of LDs exist in hepatocytes – cytosolic LDs (CLDs) and the microsomal-associated luminal LDs (LLDs)....
Apolipoprotein E (APOE) ɛ4 and Clusterin (CLU) C alleles are risk factors for Alzheimer’s disease (AD) and preclinical cognitive and memory decline in older adults. We investigated whether memory resilience to genetic risk (i.e., Apolipoprotein E [APOE] ɛ4, Clusterin [CLU] CC, and a high additive...