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Skip to Search Results- 2Bhaduri,Swayamdipta
- 1,Abdul Wasay
- 1Adam, Ibrahim S. Y.
- 1Alford, Spencer Caleb
- 1Anbukarasu, Preetam
- 1Assempour, Nazanin
- 15Department of Electrical and Computer Engineering
- 13Department of Chemistry
- 13Department of Mechanical Engineering
- 7Department of Chemical and Materials Engineering
- 2Department of Physics
- 1Department of Agricultural, Food and Nutritional Science
- 2Backhouse, Christopher (Electrical and Computer Engineering)
- 2Campbell, Robert (Chemistry)
- 2Chen, Jie (Electrical and Computer Engineering)
- 2Doucette, John (Mechanical Engineering)
- 2Elias, Anastasia (Chemical and Materials Engineering)
- 2Evoy, Stephane (Electrical and Computer Engineering)
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A novel mouse model of acute antibody-mediated transplant rejection shows simultaneous complement activating and anti-inflammatory effects of donor specific IgG antibodies
DownloadFall 2013
We developed a small animal model of pure antibody-mediated rejection (ABMR) by utilizing fully major histocompatibility complex (MHC) mismatched kidney allografts in mice. By examining resultant ABMR pathology, we show that terminal complement products C5a and C5b-9 are crucial in establishing...
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Fall 2020
Introduction: ABO-incompatible organ transplants (ABOi-Tx) recipients are at high-risk of rapid rejection mediated by ABO antibodies (ABO Abs). To manage and expand ABOi-Tx, it is necessary to understand the mechanism(s) by which natural and induced ABO Abs develop. Prior studies have used...
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An examination of linking and blocking procedures for use in deflection cantilever array-based protein detection
DownloadFall 2011
In this project common linking and blocking procedures were examined for use in multiplexed deflection cantilever array-based detection of proteins. A human interferon gamma (INF-γ) enzyme-linked immunosorbent assay (ELISA) kit was used to evaluate the effectiveness of the linking and blocking...
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Fall 2014
Carbohydrate–protein interactions play key roles in a range of biological processes. Noticeable advancements have been made in understanding the features associated with the recognition of pyranosides (six-membered ring sugars) by proteins. In contrast, similar detailed studies about the...
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Spring 2017
One of the central puzzles concerning the interaction of low Reynolds number (Re<<1) fluid transport with bacterial biomass is the formation of filamentous structures called bacterial streamer. Bacterial streamers can be tethered at one or both ends to solid surfaces, while the rest of the...
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Carbon-on-Gold Films and Spontaneous Adsorption of Aryldiazonium Salts for Surface Plasmon Resonance Sensing
DownloadFall 2021
Over the past decades, surface plasmon resonance (SPR) technology has gained popularity as a powerful analytical technique for the study of biomolecular interactions and medical diagnostics. This is made possible thanks to the well-established gold-thiolate chemistry. However, the limited...
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Fall 2010
Electro-transmittance of molecular junctions was characterized electrically and studied optically at 410nm and 532nm. Between 1kHz and 100kHz there was no qualitative difference between the control samples and the molecular junction samples, however there were difficulties with reproducibility of...
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Design and Microfabrication of Robust and Highly Integrated Thermal Lab-On-A-Chip Polymeric Systems for Genetic Diagnosis
DownloadSpring 2014
The lab-on-chip (LOC) technology could transform and greatly enhance the health care system by making genetic diagnosis tests fast, accurate and readily accessible. However, most LOC systems are not prepared to resist variations of their external environment, as they depend upon many...
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Fall 2017
The detection of biological molecules is a useful tool for diagnostics, research, and general health monitoring. By measuring concentrations of certain key components of biological samples, vital information can be gained as to the condition of the entire biological system. Diseases such as...