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Skip to Search Results- 5Field, Catherine J.
- 3Chakrabarti, Subhadeep
- 3Proctor, Spencer D.
- 3Steele, Michael A.
- 3Wu, Jianping
- 2Aguzzi, Adriano
- 70Graduate and Postdoctoral Studies (GPS), Faculty of
- 70Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 24Agricultural, Food and Nutritional Science, Department of
- 24Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 5Nursing, Faculty of
- 5Nursing, Faculty of/Health Equity
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Comparative variation within the genome of Campylobacter jejuni NCTC 11168 in human and murine hosts
Download2014
Selinger, L. Brent, Taboada, Eduardo N., Uwiera, Richard R. E., Abbott, D. Wade, Inglis, G. Douglas, Thomas, Dallas K., Lone, Abdul G.
Campylobacteriosis incited by C. jejuni is a significant enteric disease of human beings. A person working with two reference strains of C. jejuni National Collection of Type Cultures (NCTC) 11168 developed symptoms of severe enteritis including bloody diarrhea. The worker was determined to be...
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Comparing the feasibility, acceptability, clinical-, and cost-effectiveness of mental health e-screening to paper-based screening on the detection of depression, anxiety, and psychosocial risk in pregnant women: A study protocol of a randomized, parallel-group, superiority trial.
Download2014
Sword, W., Ohinmaa, A., Lasiuk, G., Giallo, R., Kingston, D., van Zanten, S., Biringer, A., Austin, M., Hegadoren, K., Lane-Smith, M., McDonald, S., MacQueen, G.
Background Stress, depression, and anxiety affect 15% to 25% of pregnant women. However, substantial barriers to psychosocial assessment exist, resulting in less than 20% of prenatal care providers assessing and treating mental health problems. Moreover, pregnant women are often reluctant to...
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Contributions of Bim and Nur77 to multiple mechanisms of T cell tolerance following high affinity antigen encounter
DownloadSpring 2015
Prevention of autoimmune disease requires the elimination or inactivation of T cells that are highly reactive to self-peptides. During T cell development in the thymus, self-reactive thymocytes undergo negative selection upon receiving a high affinity T cell receptor (TCR) signal following...
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Cree women speak: Intergenerational perspectives on weight gain during pregnancy and weight loss after pregnancy
Download2008
Brennand, Erin A., Vallianatos, Helen, Dannenbaum, David, Petawabano, Beatrice, Raine, Kim, Willows, Noreen D., Stephen, Queenie
Obesity is prevalent among the First Nations population in Canada, with serious associated health risks. Recent studies also indicate that a high percentage of First Nations women are overweight or obese at the start of their pregnancies, with a tendency to retain weight after their children are...
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Crystallization and preliminary X-ray diffraction analysis of prion protein bound to the Fab fragment of the POM1 antibody
Download2011
James, Michael N. G., Swayampakula, Mridula , Polymenidou, Magdalini , Kav, Nat N. V., Aguzzi, Adriano, Wieland, Barbara, Baral, Pravas K.
Prion diseases are neurodegenerative diseases that are characterized by the conversion of the cellular prion protein PrPc to the pathogenic isoform PrPsc. Several antibodies are known to interact with the cellular prion protein and to inhibit this transition. An antibody Fab fragment, Fab POM1,...
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Spring 2012
Human cytomegalovirus (HCMV) is implicated in several vascular diseases through endothelial dysfunction. Most of the research on CMV has focused on either congenital CMV infections or CMV disease in immunocompromised hosts; however, CMV has also been associated with vascular diseases in...
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Spring 2011
The focus of this study is to understand why, despite high uptake of antenatal care, women in Uganda continue to deliver without skilled birth attendants. A critical gap in our knowledge is an understanding of the decisions women make during pregnancy and childbirth that determine the services...
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Development of Polymeric Micelles for Site Specific Delivery of Nonsteroidal Anti-Inflammatory Drugs: Effect on the Cardiovascular Risk in an Experimental Model of Arthritis
DownloadFall 2019
Non-steroidal anti-inflammatory drugs (NSAIDs), which inhibit cyclooxygenase (COX) enzymes, are among the most widely used medications worldwide with proven efficacy in controlling inflammation and pain associated various disease conditions. The chronic systemic use of most NSAIDs, however, is...
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Digital Innovations to Support the Health and Wellbeing of Individuals with Problematic Substance Use and Substance Use Disorder
DownloadFall 2020
This dissertation explores the questions “What technology-based interventions are of most benefit in supporting the health and/or rehabilitation of individuals with substance use disorders? Where and how can they be most effectively embedded in the health system?” Chapter 1 begins with an...
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Drug-disease interaction: effect of inflammation on the pharmacological response to calcium channel blockers
DownloadFall 2010
The present research is focused on the topic of inflammation-drug interaction. Inflammation complicates many human diseases and conditions ranging from obesity to cancer. Therefore, the study of the effect of inflammation on drug pharmacokinetics and pharmacodynamics is pivotal. First, we tested...