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Fall 2010
Mast cells are immune cells important in innate immunity. Besides their role in asthma and allergies, mast cells are critical effector cells against various pathogens. Mast cells are established to be protective against bacterial infections, but little is known about their functions in viral...
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Spring 2013
Immunogenicity of intramuscular influenza vaccine is suboptimal in organ transplant recipients although intradermal vaccine may be superior by targeting dermal dendritic cells to stimulate a response. 229 patients were randomized to IM or high-dose ID vaccine during the 2010-11 season. Pre- and...
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Spring 2010
These two studies investigate the immune responses of lung and kidney transplant recipients to the influenza vaccine. The study involving kidney transplant recipients developed a novel flow cytometry assay to measure cell-mediated immunity in response to influenza vaccination. The activation of...
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The Role of Vitamin D in Anti-Tumor Necrosis Factor-Alpha-Induced Response in Patients with Inflammatory Bowel Disease
DownloadFall 2014
Vitamin D is an important immunomodulator of the immune system and has been suggested to play a role in the pathogenesis of inflammatory bowel disease (IBD). Drugs targeting TNF-alpha are effective IBD therapies, and vitamin D has been demonstrated to suppress TNF-alpha as well as work...