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Skip to Search Results- 1Anderson, Sharon
- 1Anderson, Sharon D
- 1Arvanitidis, Anastasia P
- 1Auriat, Angela Michelle
- 1Bandet, Mischa V.
- 1Caliaperumal, Jayalakshmi
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An exploration of neural network activity within the limb-associated somatosensory cortex of the healthy and stroke injured brain of mice
DownloadFall 2022
Altered somatosensation is a hallmark of incomplete recovery from stroke. Although the basic mechanisms of limb-associated somatosensation have been well studied in primates, comparatively little literature exists on the limb-associated somatosensory system of rodents. Rodent models are the...
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Fall 2021
Computed Tomography Perfusion (CTP) is a rapidly acquired minimally invasive mean to assess brain perfusion dynamics, collaterals and infarct growth in acute ischemic stroke (AIS). It helps differentiate expected stroke evolution and speed of core growth after arterial occlusion. The goals of...
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Fall 2010
Hyperthermia worsens outcome after ischemia. While it seems reasonable that hyperthermia would also worsen outcome after intracerebral hemorrhage (ICH), clinical studies attempting to find a causative relationship between hyperthermia and outcome have been inconclusive. We induced ICH with an...
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Associative plasticity and afferent regulation of corticospinal excitability in uninjured individuals and after incomplete spinal cord injury
DownloadFall 2009
Cortical representations are plastic and are allocated based on the proportional use or disuse of a pathway. A steady stream of sensory input maintains the integrity of cortical networks; while in contrast, alterations in afferent activation promote sensorimotor reorganization. After an...
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Augmenting Plasticity and Recovery from Stroke by Modulating the Extracellular Matrix of the Central Nervous System
DownloadFall 2017
Recovery following stroke occurs almost entirely in the first weeks post injury. Moreover, the efficacy of rehabilitative training is limited beyond this narrow time frame. Sprouting of spared corticospinal tract axons in the spinal cord makes a significant contribution to sensorimotor recovery,...
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Spring 2022
Carotid atherosclerosis is responsible for 15-25% of the nearly 8 million first-ever ischemic strokes that occur each year worldwide. This proportion has remained constant over the past three decades, thus suggesting that some patients with carotid atherosclerosis currently receive suboptimal...
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Central nervous system plasticity associated with pain in a mouse model of multiple sclerosis, and the antinociceptive effects of the antidepressant phenelzine
DownloadFall 2017
Multiple sclerosis (MS) is a chronic, progressive disease that involves neuroinflammation, demyelination, and neurodegeneration within the central nervous system (CNS). While loss of motor function and paralysis are considered the primary clinical consequences of MS, the disease is also...
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Spring 2010
Background: Over 80% of people who experience stroke survive, but for half, their level of activity drops significantly. Even survivors with mild disability become disengaged. Research Question: Based on an ecological model, what perceived facilitators and barriers do stroke survivors encounter...
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Fall 2016
Background: Intracerebral Hemorrhage (ICH) is associated with high morbidity and patients commonly suffer motor dysfunction. ICH volume is a significant predictor of outcome, and perihematoma edema may also represent tissue injury. Diffusion Tensor Imaging (DTI) can be used to assess in-vivo...
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Fall 2009
Stroke is a leading cause of disability in Canada. Delayed hypothermia improves outcome in patients following cardiac arrest and reduces lesion volume in rodents after transient focal ischemia, but less is known about the effectiveness of delayed hypothermia following permanent focal ischemia. In...