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Skip to Search Results- 1Alvarado, Laura
- 1Auriat, Angela Michelle
- 1Bamford, Jeremy, Andrew
- 1Bandet, Mischa V.
- 1Bergquist, Austin J
- 1Cheng,Cheng
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A pilot study investigating arm and leg FES-assisted cycling as an intervention for improving ambulation after Incomplete Spinal Cord Injury
DownloadSpring 2013
People with incomplete spinal cord injury (iSCI) have the potential for recovering walking through plasticity-induced changes in the remaining neural circuitry. Current rehabilitation for walking attempts to induce such changes by providing relevant sensory inputs and motor commands through...
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Fall 2017
Spinal cord injury (SCI) is an extremely debilitating condition, leading to sensory and motor dysfunction below the level of the injury. Presently, there are few effective treatments for SCI. This is in part due to the immense complexity of SCI pathophysiology. Thus, combined research approaches...
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An exploration of neural network activity within the limb-associated somatosensory cortex of the healthy and stroke injured brain of mice
DownloadFall 2022
Altered somatosensation is a hallmark of incomplete recovery from stroke. Although the basic mechanisms of limb-associated somatosensation have been well studied in primates, comparatively little literature exists on the limb-associated somatosensory system of rodents. Rodent models are the...
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Associative plasticity and afferent regulation of corticospinal excitability in uninjured individuals and after incomplete spinal cord injury
DownloadFall 2009
Cortical representations are plastic and are allocated based on the proportional use or disuse of a pathway. A steady stream of sensory input maintains the integrity of cortical networks; while in contrast, alterations in afferent activation promote sensorimotor reorganization. After an...
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Augmenting Plasticity and Recovery from Stroke by Modulating the Extracellular Matrix of the Central Nervous System
DownloadFall 2017
Recovery following stroke occurs almost entirely in the first weeks post injury. Moreover, the efficacy of rehabilitative training is limited beyond this narrow time frame. Sprouting of spared corticospinal tract axons in the spinal cord makes a significant contribution to sensorimotor recovery,...
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Spring 2010
Maintaining balance is controlled by two different processes: feedforward and feedback control. Feed-forward control is used prior to performing voluntary movements whereas feedback control is used to correct for unexpected perturbations. Studies suggested that age-related changes in postural...
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Central nervous system plasticity associated with pain in a mouse model of multiple sclerosis, and the antinociceptive effects of the antidepressant phenelzine
DownloadFall 2017
Multiple sclerosis (MS) is a chronic, progressive disease that involves neuroinflammation, demyelination, and neurodegeneration within the central nervous system (CNS). While loss of motor function and paralysis are considered the primary clinical consequences of MS, the disease is also...
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Clinical Utility of Proposed Gait Stability Measures: Selection, Application and Evaluation of the Extrapolated Centre of Mass
DownloadSpring 2019
Gait stability is the ability to maintain a state of equilibrium during locomotion. In humans, this includes the need to maintain a stable walking pattern while regularly positioning the body in a state of imbalance. Thus, it is not surprising that gait is accompanied by an increased risk of...
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Development of Surrogate Spinal Cords for the Evaluation of Electrode Arrays Used in Intraspinal Implants
DownloadSpring 2012
A surrogate spinal cord was developed to test the mechanical stability of electrode arrays for intraspinal implants. The mechanical and surface properties of candidate materials were tested. The elastic modulus was characterized using dynamic mechanical analysis. Forces required to indent the...
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External sensors for the feedback control of functional electrical stimulation assisted walking
DownloadFall 2010
Functional electrical stimulation (FES) is a rehabilitative technology that can be used to improve walking in individuals with mobility impairments due to neurologic injury or disease. Feedback is essential for efficient FES-assisted walking. The overall goal of my project was to investigate...