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Skip to Search Results- 16Graduate and Postdoctoral Studies (GPS), Faculty of
- 16Graduate and Postdoctoral Studies (GPS), Faculty of /Theses and Dissertations
- 5Biological Sciences, Department of
- 5Biological Sciences, Department of/Journal Articles (Biological Sciences)
- 4Biochemistry, Department of
- 4Biochemistry, Department of/Journal Articles (Biochemistry)
- 5Department of Biological Sciences
- 2Department of Biochemistry
- 1Department of Cell Biology
- 1Department of Civil and Environmental Engineering
- 1Department of Genetics
- 1Department of Medical Microbiology and Immunology
- 2Waskiewicz, Andrew (Biological Sciences)
- 1Boliek, Carol (Speech-Language Pathology and Audiology)
- 1Burshtyn, Deborah (Department of Medical Microbiology and Immunology)
- 1Campbell, Shelagh (Biological Sciences)
- 1Cummine, Jacqueline (Speech-Language Pathology and Audiology)
- 1Dr. Ania Ulrich (Civil and Environmental Engineering)
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A role for the nuclear pore complex protein Nup170p in defining chromatin structure and regulating gene expression
DownloadSpring 2012
The spatial organization of chromosomal loci within the nucleus can have a significant influence on transcriptional activity. Transcriptionally active genes are generally positioned within the nuclear interior. By contrast, the positioning of genes at the nuclear periphery is often correlated...
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Activation of Delayed and Fluid Petroleum Coke for the Adsorption and Removal of Naphthenic Acids from Oil Sands Tailings Pond Water
DownloadSpring 2011
Oil sands companies produce substantial quantities of tailings known to contain high concentrations of dissolved organic by-products. The use of petroleum coke was proposed as a potential adsorbent for organic contaminant removal from tailings pond water. Physical activation was used to create a...
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Spring 2015
Besides being the most popular drug in the world, caffeine is an attractive tool used in research to help us answer fascinating scientific questions, because caffeine impinges on a number of molecular pathways. In my research, I used caffeine to study DNA repair pathways and insect xenobiotic...
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Chk1 and Wee1 kinases coordinate DNA replication, chromosome condensation and anaphase entry
Download2012
Campbell, S.D., Homola, E.M., Fasulo, B., Yu, K.R., Hsieh, T.S., Sullivan, W., Koyama, C.
Defects in DNA replication and chromosome condensation are common phenotypes in cancer cells. A link between replication and condensation has been established, but little is known about the role of checkpoints in monitoring chromosome condensation. We investigate this function by live analysis,...
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Copresentation of antigen and ligands of Siglec-G induces B cell tolerance independent of CD22
2013
Pfrengle, F., Kawasaki, N., Paulson, J. C. , Macauley, M. S.
Differentiation of self from nonself is indispensable for maintaining B cell tolerance in peripheral tissues. CD22 and Siglec-G (sialic acid-binding Ig-like lectin G) are two inhibitory coreceptors of the BCR that are implicated in maintenance of tolerance to self Ags. Enforced ligation of CD22...
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COUP-TF1 antagonizes Nkx25-mediated activation of the calreticulin gene during cardiac development
Download2001-01-01
Guo, Lei, Lynch, Jeffrey, Nakamur, Kimitoshi, Fliegel, Larry, Kasahara, Hideko, Izumo, Seigo, Komuro, Issei, Agellon, Luis B., Michalak, Marek
Calreticulin, a Ca2+ binding chaperone of the endoplasmic reticulum, is also highly expressed in the embryonic heart, and knockout of the calreticulin gene is lethal during embryogenesis because of impaired cardiac development. The protein is down-regulated after birth, and elevated expression of...
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Goldfish ghrelin: Molecular characterization of the complementary deoxyribonucleic acid, partial gene structure and evidence for its stimulatory role in food intake
Download2002
Rivier, J., Kaiya, H., Lin, X.W., Cervini, L., Unniappan, S., Peter, R.E., Kangawa, K.
Complementary deoxyribonucleic acid (cDNA) encoding goldfish preproghrelin was identified using rapid amplification of the cDNA ends (RACE) and reverse transcription (RT)-polymerase chain reaction (PCR). The 490 bp cDNA encodes a 103 amino acid preproghrelin which has a 26 amino acid signal...
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High resolution optical tweezers for single molecule studies of hierarchical folding in the pbuE riboswitch aptamer
DownloadSpring 2010
Riboswitches are gene regulatory elements found in messenger RNA that function by changing structure upon the binding of a ligand to an aptamer domain. Single adenine-binding pbuE riboswitch aptamer RNAs were unfolded and refolded co-transcriptionally using optical tweezers for single molecule...
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Investigation of an enhancer-based regulation of LILRB1 gene and the differential functions of LILRB1 variants in natural killer cells
DownloadFall 2020
Human cytomegalovirus (HCMV) causes severe disease in immunocompromised people such as transplant patients. NK cells are crucial in controlling HCMV whereas HCMV developed multiple strategies to evade NK cell surveillance. HCMV encodes a human MHC-I homolog called UL18 to target an inhibitory...