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Skip to Search Results- 1Brophy, Taylor Raymond
- 1Chu, Kevin
- 1Clifford, Alexander M
- 1Collins, Catherine Elizabeth Victoria
- 1Corscadden, Lisa.
- 1Cyr, Anika
- 6Department of Agricultural, Food, and Nutritional Science
- 3Department of Biological Sciences
- 3Department of Medicine
- 2Department of Medical Microbiology and Immunology
- 2Department of Physiology
- 2Faculty of Pharmacy and Pharmaceutical Sciences
- 1Baker, Glen (Psychiatry)
- 1Davidge, Sandra T. (Physiology/Obstetrics and Gynecology)
- 1Dr. Andrew Mason (Medicine)
- 1Dr. David Bressler (Agricultural, Food and Nutritional Science)
- 1Dr. Dion R. Brocks, Faculty of Pharmacy and Pharmaceutical Sciences
- 1Dyck, Jason RB (Pediatrics)/ McAlister, Finlay A (Medicine)
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The effect of oral lipids and lipoproteins on the biodistribution, metabolism and electrocardiographic side-effects of halofantrine
DownloadSpring 2011
In the past, hyperlipidemia (HL) has been shown to affect the pharmacokinetic and pharmacodynamic properties of lipophilic drugs extensively bound to lipoproteins, including halofantrine (HF). The present thesis examined the effect of HL on the biodistribution, metabolism and electrocardiographic...
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Spring 2013
Glucose is the sole fuel for the brain in normal physiological conditions. Absence of glucose or its presence in high concentrations has been shown to be harmful to neurons. Microglia, the innate immune cells of the brain, are the first line of defense against changes in the CNS environment and...
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The Effects of Hydraulic Fracturing Flowback and Produced Water on Exercise Capacity and Metabolic Fuel Selection in Rainbow Trout (Oncorhynchus mykiss)
DownloadFall 2022
Hydraulic fracturing is an increasingly popular technique for unconventional hydrocarbon extraction in Canada. As its popularity continues to grow, concerns are being raised regarding its waste product, hydraulic fracturing flowback and produced water (FPW), and its effects on the environment....
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The interaction of phenelzine with human monoamine oxidase B: characterization and consequences
DownloadSpring 2022
Phenelzine (PLZ) is a monoamine oxidase (MAO) inhibitor developed in the 1960s which has been used clinically for psychiatric conditions such as depression and anxiety disorders. However, despite over 60 years of research, the mechanism by which PLZ exerts its effects on MAO has yet to be...