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Skip to Search Results- 2Borthwick, Faye
- 2Hassanali, Zahra
- 2Mangat, Rabban
- 2Proctor, Spencer D.
- 2Russell, James C.
- 2Vine, Donna F.
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Arterial retention of remnant lipoproteins ex-vivo is increased during insulin resistance due to increased arterial biglycan and production of cholesterol-rich atherogenic particles, that can be improved by ezetimibe in the JCR:LA-cp rat
Download2012
Russell, James C., Proctor, Spencer D., Uwiera, Richard R. E., Vine, Donna F., Mangat, Rabban, Hassanali, Zahra, Cheeseman, Christopher I., Borthwick, Faye, Warnakula, Samantha
Background Literature supports the “response-to-retention” hypothesis—that during insulin resistance, impaired metabolism of remnant lipoproteins can contribute to accelerated cardiovascular disease progression. We used the JCR:LA-cp rat model of metabolic syndrome (MetS) to determine the extent...
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Chronic dietary n-3 PUFA intervention improves dyslipidaemia and subsequent cardiovascular complications in the JCR:LA-cp rat model of the metabolic syndrome
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Borthwick, Faye, Field, Catherine J., Wang, Ye, Proctor, Spencer D., Jaeschke, Anja, Shi, Danni, Hassanali, Zahra, Ruth, Megan, Russell, James C., Mangat, Rabban, Vine, Donna F., Lu, Jing
There is increasing interest in the potential chronic beneficial effects of dietary n-3 PUFA on the metabolic syndrome (MetS) and associated cardiovascular complications. We have recently established that increased dietary n-3 PUFA has a profound acute benefit on fasting lipids and the...