Search
Skip to Search Results-
2005
Stothard, P., Lu, P., Cruz, J.A., Szafron, D., Van Domselaar, G.H., Shrivistava, S., Guo, A., Dong, X., Grenier, R., Wishart, D.S.
BASys (Bacterial Annotation System) is a web server that supports automated, in-depth annotation of bacterial genomic (chromosomal and plasmid) sequences. It accepts raw DNA sequence data and an optional list of gene identification information and provides extensive textual annotation and...
-
Coordinated international action to accelerate genome-to-phenome with FAANG, the Functional Annotation of Animal Genomes project
Download2015
Tosser-Klopp, G., Zhou, H., Palti, Y., Nanduri, B., Tixier-Boichard, M., Silverstein, J., Plastow, G. S., Sarropoulou, E., Brauning, R., Zhao, S., Rohrer, G. A., Elsik, C. G., Cheng, H. H., Giuffra, E., Notredame, C., Khatib, H., Vilkki, J., Couldrey, C., Archibald, A. L., Tellam, R. L., Schmidt, C. J., Reecy, J. M., Clarke, L., Huang, L. S., Groenen, M. A., McEwan, J. C., Burt, D. W., Kim, H., Bottema, C. D., Kijas, J. W., Dalrymple, B. P., White, S. N., Burgess, S. C., Hayes, B. J., McCarthy, F. M., Moore, S., Foissac, S., Lunney, J. K., Andersson, L., Tuggle, C. K., Casas, E.
We describe the organization of a nascent international effort, the Functional Annotation of Animal Genomes (FAANG) project, whose aim is to produce comprehensive maps of functional elements in the genomes of domesticated animal species.
-
Dominant Red Coat Color in Holstein Cattle Is Associated with a Missense Mutation in the Coatomer Protein Complex, Subunit Alpha (COPA) Gene
Download2015
Sällman Almén, M., Liao, X., Stothard, P., Henegar, C., Van Doormaal, B., Rubin, C. -J., Andersson, L., Barsh, G. S., Ito, S., Plastow, G., Wakamatsu, K., Dorshorst, B.
Coat color in Holstein dairy cattle is primarily controlled by the melanocortin 1 receptor (MC1R) gene, a central determinant of black (eumelanin) vs. red/brown pheomelanin synthesis across animal species. The major MC1R alleles in Holsteins are Dominant Black (MC1RD) and Recessive Red (MC1Re). A...
-
Expansion of ruminant-specific microRNAs shapes target gene expression divergence between ruminant and non-ruminant species
Download2013
Kommadath, A., Bao, H., Meng, Y., Plastow, G. S., Stothard, P., Sun, X., Arantes, A. S., Guan, L. L.
Background Understanding how species-specific microRNAs (miRNAs) contribute to species-specific phenotypes is a central topic in biology. This study aimed to elucidate the role of ruminant-specific miRNAs in shaping mRNA expression divergence between ruminant and non-ruminant species. ...
-
High resolution radiation hybrid maps of bovine chromosome 19 and 29 and comparison with the bovine genome sequence assembly
Download2007
Murdoch, B., Wang, Z., Stothard, P., Womack, J. E., Mckay, S. D., Moore, S. S., Schiex, T., Prasad, A.
Background High resolution radiation hybrid (RH) maps can facilitate genome sequence assembly by correctly ordering genes and genetic markers along chromosomes. The objective of the present study was to generate high resolution RH maps of bovine chromosomes 19 (BTA19) and 29 (BTA29), and...
-
1988
Plastow, G. S., Mileham, A. J., Siggens, K. W.
A 3.8 kb male specific fragment was observed following agarose gel etectrophoresis of porcine DNA digested with Sph I. DNA was recovered from this region of a gel using DE-81 paper and ligated to Sph I digested pUC18. Plasmids carrying male specific sequences were identified by their differential...
-
2014
Plastow, G., Stothard, P., Moore, S., Bao, H., Meng, Y., Liao, X.
Gene duplication is a widespread phenomenon in genome evolution, and it has been proposed to serve as an engine of evolutionary innovation. In the present study, we performed the first comprehensive analysis of duplicate genes in the bovine genome. A total of 3131 putative duplicated gene pairs...