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Skip to Search Results- 4Dennis, Jonathan J.
- 3Lynch, Karlene H.
- 3Stothard, Paul
- 2Seed, Kimberley D.
- 1Finlay, Warren H.
- 1Golshani, Laleh
- 2Cystic-Fibrosis
- 2Proteins
- 2Pseudomonas-Cepacia
- 2Translational Frameshift
- 1Aerosols
- 1Antibiotic-Resistance
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Comparative analysis of two phenotypically-similar but genomically-distinct Burkholderia cenocepacia-specific bacteriophages
Download2012
Stothard, Paul, Dennis, Jonathan J., Lynch, Karlene H.
Background Genomic analysis of bacteriophages infecting the Burkholderia cepacia complex (BCC) is an important preliminary step in the development of a phage therapy protocol for these opportunistic pathogens. The objective of this study was to characterize KL1 (vBBceSKL1) and AH2 (vBBceSAH2),...
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Genome sequence and activity of KS10, a transposable phage of the Burkholderia cepacia complex
Download2008
Lynch, Karlene H., Shrivastava, Savita, Seed, Kimberley D., Goudie, Amanda D., Wishart, David S., Stothard, Paul, Dennis, Jonathan J.
Background The Burkholderia cepacia complex (BCC) is a versatile group of Gram negative organisms that can be found throughout the environment in sources such as soil, water, and plants. While BCC bacteria can be involved in beneficial interactions with plants, they are also considered...
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2010
Dennis, Jonathan J., Stothard, Paul, Lynch, Karlene H.
Background The Burkholderia cepacia complex (BCC) is comprised of at least seventeen Gram-negative species that cause infections in cystic fibrosis patients. Because BCC bacteria are broadly antibiotic resistant, phage therapy is currently being investigated as a possible alternative treatment...
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Toward Modern Inhalational Bacteriophage Therapy: Nebulization of Bacteriophages of Burkholderia cepacia Complex
Download2008
Dennis, Jonathan J., Finlay, Warren H., Golshani, Laleh, Seed, Kimberley D.
Antibiotic-resistant bacterial infections have renewed interest in finding substitute methods of treatment. The purpose of the present in vitro study was to investigate the possibility of respiratory delivery of a Burkholderia cepacia complex (BCC) bacteriophage by nebulized aerosol...