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- 2Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 1Agricultural, Food and Nutritional Science, Department of
- 1Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
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Airborne particulate matter and a western style diet as potential environmental factors in the pathogenesis of Inflammatory Bowel Disease
DownloadFall 2012
Inflammatory bowel disease is believed to occure in response to environmental factors resulting in immune dysregulation in genetically predisposed individuals. Such environmental factors include diet, (specifically a “western diet”rich in refined sugars, and fat) and airborne particulate matter...
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Environmental Exposures, Gut Microbiota, and Urinary Metabolomic Fingerprint of Crohn’s Disease Patients Who Have Undergone Ileo-colonic Resection
DownloadSpring 2014
Inflammatory bowel disease (IBD) is an idiopathic disease that causes intestinal inflammation and lesions. Canada has one of the highest rates of IBD in the world. One of the major types of IBD is Crohn’s Disease (CD) and a large portion of CD patients will undergo surgical resection in the...
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Environmental particulate matter induces murine intestinal inflammatory responses and alters the gut microbiome
Download2013-01-01
Thiesen, Aducio, Rioux, Kevin P., Tso, Robert, Kish, Lisa, Barkema, Herman W., Madsen, Karen L., Vincent, Renaud, Wine, Eytan, Kaplan, Gilaad G., Hotte, Naomi, Gänzle, Michael G.
Background Particulate matter (PM) is a key pollutant in ambient air that has been associated with negative health conditions in urban environments. The aim of this study was to examine the effects of orally administered PM on the gut microbiome and immune function under normal and inflammatory...