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Role of Glutamate and GABA in a mouse model expressing mutant human APP in the absence of NPC1 protein
DownloadSpring 2013
Cholesterol plays a critical role in Alzheimer’s disease (AD) pathogenesis, but the underlying mechanisms remain unclear. To address this issue we have generated a line of ANPC transgenic mice that overexpress mutant-human amyloid precursor protein in the absence of cholesterol transporting...
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