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Skip to Search Results- 4Ghosh, Sunita
- 3Prado, Carla M.
- 3Winter, Philip
- 2Darestani, Reza R.
- 2Kitova, Elena N.
- 2Klassen, John S.
- 3Agricultural, Food and Nutritional Science, Department of
- 3Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 2Chemistry, Department of
- 2Chemistry, Department of/Journal Articles (Chemistry)
- 1Oncology, Department of
- 1Oncology, Department of/Medical Oncology
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Ability of Anthropometric Measurements to Predict Metabolic Health among Patients in Alberta: A Cross-sectional Study in Primary Care
Download2023-03-08
Ghosh, Sunita, Purcell, Sarah A., Martin, Ken, Lima, Isac, Prado, Carla M.
Purpose: This study compared anthropometric and body fat percent (BF%) equations in relation to measures of metabolic health. Methods: BF% calculations (Bergman, Fels, and Woolcott) and anthropometric measurements were used to determine obesity among a sample of patients attending primary care in...
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2016-12-09
Winter, Philip, Wang, Xumin, Mackey, John R. , Lee, John C. , Wong, Gane Ka-Shu, Ghosh, Sunita, Patterson, Jordan, Zhang, Hangxiao, Wang, Weiwei, Tuszynski, Jack A. , Katsetos, Christos D., Graham, Kathryn, Luduena, Richard F.
Tubulin is the target for very widely used anti-tumor drugs, including Vinca alkaloids, taxanes, and epothilones, which are an important component of chemotherapy in breast cancer and other malignancies. Paclitaxel and other tubulin-targeting drugs bind to the β subunit of tubulin, which is a...
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Protein Recommendation to Increase Muscle (PRIMe): Study protocol for a randomized controlled pilot trial investigating the feasibility of a high protein diet to halt loss of muscle mass in patients with colorectal cancer
Download2021-02-01
Ford, Katherine L., Sawyer, Michael B., Trottier, Claire F., Ghosh, Sunita, Deutz, Nicolaas E. P., Siervo, Mario, Porter Starr, Kathryn N., Bales, Connie W., Disi, Ilana Roitman, Prado, Carla M.
Background Severe muscle mass (MM) loss is a defining feature of cancer observed across all types and stages of disease and is an independent predictor of poor clinical outcomes including higher incidences of chemotherapy toxicity and decreased survival. Protein is essential to build MM, yet the...
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Screening anti-cancer drugs against tubulin using catch-and-release electrospray ionization mass spectrometry
Download2016
Kitova, Elena N., Klassen, John S., Winter, Philip, Tuszynski, Jack A., Darestani, Reza R.
Tubulin, which is the building block of microtubules, plays an important role in cell division. This critical role makes tubulin an attractive target for the development of chemotherapeutic drugs to treat cancer. Currently, there is no general binding assay for tubulin–drug interactions. The...
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Screening anti-cancer drugs against tubulin using catch-and-release electrospray ionization mass spectrometry
Download2016
Kitova, Elena N., Klassen, John S., Winter, Philip, Tuszynski, Jack A., Darestani, Reza R.
Tubulin, which is the building block of microtubules, plays an important role in cell division. This critical role makes tubulin an attractive target for the development of chemotherapeutic drugs to treat cancer. Currently, there is no general binding assay for tubulin–drug interactions. The...
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Skeletal muscle anabolism is a side effect of therapy with the MEK inhibitor: Selumetinib in patients with cholangiocarcinoma
Download2012
Ghosh, Sunita, Doyle, L. Austin, Baracos, Vickie E., Prado, Carla M., Sawyer, Michael B., Bekaii-Saab, Tanios, Shrestha, Suraj
background: Cancer cachexia is characterised by skeletal muscle wasting; however, potential for muscle anabolism in patients with advanced cancer is unproven. methods: Quantitative analysis of computed tomography images for loss/gain of muscle in cholangiocarcinoma patients receiving selumetinib...