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Cyanogenic glycosides are secondary plant compounds that are widespread in the plant kingdom. Their biosynthesis starts with the conversion of aromatic or aliphatic amino acids into their respective aldoximes, catalysed by N-hydroxylating cytochrome P450 monooxygenases (CYP) of the CYP79 family....
Winter, Philip, Wang, Xumin, Mackey, John R. , Lee, John C. , Wong, Gane Ka-Shu, Ghosh, Sunita, Patterson, Jordan, Zhang, Hangxiao, Wang, Weiwei, Tuszynski, Jack A. , Katsetos, Christos D., Graham, Kathryn, Luduena, Richard F.
Tubulin is the target for very widely used anti-tumor drugs, including Vinca alkaloids, taxanes, and epothilones, which are an important component of chemotherapy in breast cancer and other malignancies. Paclitaxel and other tubulin-targeting drugs bind to the β subunit of tubulin, which is a...
Duggan, Thomas, Broadhurst, David I., St. George, M., Sacher, Jessica, Sykes, B.D., Curtis, Jonathan M., Wu, Fang, Quiroga, Ariel, Daude, N., Afzal Javed, M., Kovalchuk, O., Wishart, D., Arutyunov, Denis, Li, Liang, Wong, Gane Ka-Shu, Cass, C., Stuart, David, Glaves, J.P., Simpson, David, Fahlman, Richard P., Lehner, Richard, Wishart, David S., Westaway, D., Kramer, David, Lai, Raymond, Szymanski, Christine M., Damaraju, Sambasivarao, Tuszynski, J.
Includes presentation abstracts for authors listed as well as abstracts for posters by K. Marx, A. Kiehne, M. Meyer; Saifur R. Khan, Argishti Baghdasarian, Richard P. Fahlman, Arno G. Siraki; S.N. Reinke, D.I. Broadhurst, C. Power; Shereen A. Elbayomy, Mark T. McDermott; Simon Ng, Mohammad R....