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- 2Hegele, Robert A.
- 2Young, T. Kue
- 1Anand, Sonia S.
- 1Anderson, Carol
- 1Ban, Matthew R.
- 2Nunavut
- 1Allele carrier
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Association between the -455T>C promoter polymorphism of the APOC3 gene and the metabolic syndrome in a multi-ethnic sample
Download2007-12-20
Pollex, Rebecca L., Ban, Matthew R., Young, T. Kue, Bjerregaard, Peter, Anand, Sonia S., Yusuf, Salim, Zinman, Bernard, Harris, Stewart B., Hanley, Anthony J. G., Connelly, Philip W., Huff, Murray W., Hegele, Robert A.
"Background: Common polymorphisms in the promoter of the APOC3 gene have been associated with hypertriglyceridemia and may impact on phenotypic expression of the metabolic syndrome (MetS). The rs7566605 marker, located near the INSIG2 gene, has been found to be associated with obesity, making it...
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1999-08-04
Hegele, Robert A., Anderson, Carol, Young, T. Kue, Connelly, Philip W.
"The GNB3 825T allele encodes a product that has enhanced activation of heterotrimeric G proteins in vitro and could play a role in adipogenesis. We therefore evaluated the possibility that the GNB3 825T allele was associated with obesity in a sample of 213 healthy Canadian Inuit. We found that...