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Skip to Search Results- 827Medicine and Dentistry, Faculty of
- 559Medicine and Dentistry, Faculty of/Medical Laboratory Science, Division of
- 107Medicine and Dentistry, Faculty of/Oral Health
- 50Medicine and Dentistry, Faculty of/Journal Articles (Medicine and Dentistry)
- 42Medicine and Dentistry, Faculty of/Alberta Research Centre for Health Evidence (ARCHE)
- 34Medicine and Dentistry, Faculty of/Medical Education
- 558Villatoro, Valentin (Supervisor)
- 283Kwon, Gloria
- 256To, Michelle
- 249Fraser, Marion
- 42Andrew Hoang
- 22Hartling, L.
- 549Hematology
- 459Romanowsky Stain
- 280Peripheral Blood Smear
- 119Bone Marrow
- 90Neutrophil
- 52Bone Marrow Smear
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Stereo-selective deuteration in aspartate, asparagine, lysine, and methionine amino acid residues using fumarate as a carbon source for E. coli in D2O
Download2017-01-01
Danmaliki, Gaddafi I., Liu, Philip B., Hwang, Peter M.
We propose an isotope labeling strategy for expressing proteins in E. coli using protonated natural abundance 12C carbon sources in D2O. The strategy eliminates dominant 1H-13C and 1H-1H dipolar relaxation mechanisms to produce long-lived magnetization for solution NMR spectroscopy. Isolated 1H...
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Steroids and bronchodilators for acute bronchiolitis in the first two years of life: systematic review and meta-analysis.
Download2011
Bialy, L., Klassen, T. P., Hartling, L., Vandermeer, B., Johnson, D., Milne, A., Plint, A., Fernandes, R. M.
Objective To evaluate and compare the efficacy and safety of bronchodilators and steroids, alone or combined, for the acute management of bronchiolitis in children aged less than 2 years. Design Systematic review and meta-analysis. Data sources Medline, Embase, Central, Scopus, PubMed, LILACS,...
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Storytelling as a communication tool for health consumers: development of an intervention for parents of children with croup. Stories to communicate health information.
Download2010
Hartling, L., Johnson, D., Scott, S. D., Bishop, T., Klassen, T. P., Pandya, R.
BACKGROUND: Stories may be an effective tool to communicate with and influence patients because of their ability to engage the reader. The objective of this paper is to describe the development of a story-based intervention for delivery of health evidence to parents of children with croup for use...
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Structure and Function of Cardiac Troponin C (TNNC1): Implications for Heart Failure, Cardiomyopathies, and Troponin Modulating Drugs
Download2015-01-01
Li, Monica X., Hwang, Peter M.
In striated muscle, the protein troponin complex turns contraction on and off in a calcium-dependent manner. The calcium-sensing component of the complex is troponin C, which is expressed from the TNNC1 gene in both cardiac muscle and slow-twitch skeletal muscle (identical transcript in both...
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Structure and proteolytic susceptibility of the inhibitory C-terminal tail of cardiac troponin I
Download2019-01-01
Mahmud, Zabed, Zahran, Somaya, Liu, Philip B., Reiz, Bela, Chan, Brandon Y.H., Roczkowsky, Andrej, McCartney, Christian-Scott E., Davies, Peter L., Li, Liang, Schulz, Richard, Hwang, Peter M.
Background Cardiac troponin I (cTnI) has two flexible tails that control the cardiac cycle. The C-terminal tail, cTnI135-209, binds actin to shut off cardiac muscle contraction, whereas the competing calcium-dependent binding of the switch region, cTnI146-158, by cardiac troponin C (cTnC)...
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2016-01-01
Cai, Fangze, Li, Monica X., Pineda-Sanbria, Sandra E., Gelozia, Shorena, Lindert, Steffen, West, Frederick, Sykes, Brian D., Hwang, Peter M.
In cardiac and skeletal muscle, the troponin complex turns muscle contraction on and off in a calcium-dependent manner. Many small molecules are known to bind to the troponin complex to modulate its calcium binding affinity, and this may be useful in a broad range of conditions in which striated...