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IDENTIFYING ADOLESCENTS AT RISK OF DEVELOPING NEGATIVE OUTCOMES AFTER RECEIVING OPIOID ANALGESICS FOR CHRONIC NON-CANCER PAIN MANAGEMENT USING MACHINE LEARNING ALGORITHMS
DownloadSpring 2023
Canada's prescription opioid dispensing rates have increased since the early 21st century and this has contributed to an increase in opioid-related morbidity and mortality. Adolescents are one of the most vulnerable age groups when it comes to experiencing morbidity and mortality related to...
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Spring 2023
The increased availability and use of assisted reproductive technologies, legislative changes that recognize equal marriage, and the expansion of legal parentage beyond “the rule of two” are inviting Canadians to reimagine fundamental questions about kinship, parentage, and legal recognition. My...
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Spring 2023
As of 2016, the global annual production of plastic was 330 million metric tonnes (Plastics Europe, 2017). This staggering number is expected to double over the next 20 years as consumption increases (Plastics Europe, 2017; Lebreton et al., 2019). Less than half of the plastic produced reaches a...
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Obtaining Temperature Dependence of Cell Membrane Permeability Parameters Using Non-Ideal Thermodynamic Assumptions to Mathematically Model Real Cryopreservation Protocols
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Cryopreservation is the process of preserving biological matter such as cells, tissues, and organs, at sub-zero temperatures for long-term storage. Cells at low temperatures are susceptible to mechanical damage due to intracellular ice formation and osmotic injuries related to increasing...
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Spring 2023
Coral reefs are essential to the marine ecosystem, and provide some of the most diverse habitats in the world. Coral reef fisheries contribute 6.8 billion to the economy a year globally. However, coral reefs are under significant threat because of human activities such as overfishing, ocean...
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Spring 2023
Emulsion droplets are present in various systems and their dynamic behaviors are important to the design of efficient processes in different biological and industrial applications. Studying the interaction mechanisms of deformable droplets provides fundamental insights into many unsolved problems...
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Spring 2023
In this thesis, rare-earth-containing chalcogenides and oxychalcogenides were sought with the aim to identify new crystal structures and to evaluate their potential as optical and thermoelectric materials. They were synthesized in the form of pure microcrystalline powders and single crystals...
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Developmental Programming of Cardiac and Coronary Artery Dysfunction in Adult Male and Female Offspring Exposed to Prenatal Hypoxia
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Cardiovascular disease is a leading cause of global mortality and a major contributor to morbidity worldwide. Early epidemiological studies demonstrated that pregnancy complications can impact the health of the offspring in adult life. Fetal hypoxia is one of the most common complications of...
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Experimental Tight Rock Characterization and Surfactant Screening for Hydraulic Fracturing Operations
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Recently, unconventional resources, especially tight and shale reservoirs, have developed rapidly because of advances in horizontal drilling technologies and hydraulic fracturing technique. Based on the annual energy outlook of the Energy Information Administration, tight oil production in the US...
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Developing Penetration Rate Prediction Models to Enhance the Productivity Prediction of Microtunneling Construction Projects
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Predicting the productivity of microtunnelling construction projects is challenging due to the inherent complexities of this trenchless excavation method. One of these complexities has to do with estimating the micro-tunnel boring machine penetration rate, given that it is subject to a number of...