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2009

Field, Catherine J., Schnabl, Kareena L., Clandinin M. Thomas

Gangliosides are glycosphingolipids found in cell membranes and human milk with important roles in cell proliferation, differentiation, growth, adhesion, migration, signalling and apoptosis. Similar changes in ganglioside composition occur during embryonic development, lactation and cancer cell...

2004

Lopaschuk, G., Ezekowitz, C., Armstrong, P.W., Michelakis, E., Seldon, R., Ghali, W.A., Archer, S., Anderson, T., Jensen, L., Hayward, R.

Cardiovascular research training is experiential, and \"skills\" are traditionally acquired through a master-apprentice paradigm. The complexity of contemporary clinical research requires a new model for research training. Facilitated through a Strategic Training Program Initiative, the Canadian...

2001

MacLean, Melissa A., Zalkovic, Pavol, Ambrose, Divakar J.

Abstract A procedure to secure a jugular vein catheter system to the neck of cattle is described. A wide-mouthed polypropylene bottle attached to a halter strap provided a secure container for the catheter. This device allowed convenient access to the catheter for repeated sampling and,...

1998

Day, B. W., Reha-Krantz, L., Shukla, R., Melacrinos, A., Keohavong, P.

Abstract: In vitro DNA replication by exonuclease-deficient T7 DNA polymerase (Sequenase) and an exonuclease deficient T4 DNA polymerase was examined on a 244-nucleotide DNA template treated with three electrophilic polycyclic aromatic hydrocarbon (PAH) metabolites: racemic...

2012

Naeth, M. A., Raab, T., Bens, O., Krümmelbein, J.

Germany is the world’s leading lignite coal producer. The region surrounding the towns of Cottbus and Senftenberg in Lusatia, Eastern Germany, is one of the largest mining areas in Germany, and has economically been strongly dependent on lignite mining and lignite processing industries since the...

2012

Klassen, John S., Lin, Hong, Kitova, Elena N., Ng, Kenneth K., Johnson, M. A., Eugenio, Luiz

Electrospray ionization mass spectrometry (ESI-MS) measurements were performed under a variety of solution conditions on a highly acidic sub-fragment (B3C) of the C-terminal carbohydrate-binding repeat region of Clostridium difficile toxin B, and two mutants (B4A and B4B) containing fewer acidic...

2013

Greta G. Cummings, Leslie Hayduk, Janet E. Squires, Carole A. Estabrooks, Lisa A. Cranley, Alison M. Hutchinson, Peter G. Norton, Mark Gierl

Background and Purpose. In this paper, we present a protocol for advanced psychometric assessments of surveys based on the Standards for Educational and Psychological Testing. We use the Alberta Context Tool (ACT) as an exemplar survey to which this protocol can be applied. Methods. Data mapping,...

2014

Elliott, J., Stolee, P., Chesworth, B. M., Ceci, C., Forbes, D

INTRODUCTION: Following hip fracture surgery, patients often experience multiple transitions through different care settings, with resultant challenges to the quality and continuity of patient care. Family caregivers can play a key role in these transitions, but are often poorly engaged in the...

1960

Morgenstern, N. R., Bishop, A. W.

The application of the effective stress analysis to earth slopes has suffered through lack of a general solution such as that presented by Taylor (1937) for the total stress analysis. Recent developments in computing technique have been applied to the slip circle method and have made it possible...

2008

O'Sullivan, N.P., Wong, G.K., Lawley, C.T., McKay, J.C., Groenen, M.A., Fulton, J.E., Crooijmans, R.P., Muir, W.M., Megens, H.J., Cheng, H.H., McLeod, S., Zhang, H.M., Zhang, Y., Albers, G.A.A., Delany, M.E., Settar, P., Okimoto, R., Vereijken, A., Wang, J., Jungerius-Rattink, A.

In 2004 the chicken genome sequence and more than 2.8 million single nucleotide polymorphisms (SNPs) were reported. This information greatly enhanced the ability of poultry scientists to understand chicken biology, especially with respect to identification of quantitative trait loci (QTL) and...