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Cumulative Total Incidence for Estimating the Burden of Recurrent Events and Risk vs. Rate Concepts and Regression Models in Epidemiology
DownloadFall 2013
In the first part of this thesis, a straightforward intuitive method for descriptive survival analysis, termed “cumulative total incidence”, is proposed to measure the total burden of recurrent events in a population by a given time. Using data from the Childhood Cancer Survivor Study,...
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Identification of Shared and Distinct Gene-disease Associations Among Multiple Related Diseases and Multiple Subtypes of a Disease
DownloadFall 2013
Genome-wide association study (GWAS) is an approach with high-throughput genotyping to uncover genetic susceptibilities of complex diseases. However, the genetic susceptibilities discovered usually carry very small risk increments. Additionally, the current approach to assess whether these...
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