Search
Skip to Search Results- 2Sharma, Vishal
- 1Achtymichuk, Karly A
- 1Aidoo, Henry K
- 1Akpinar, Ayse I
- 1Al Amin, Saad Ullah
- 1Alaazi, Dominic A
-
Long-term Healthcare Transition Pathways Among Community Dwelling Adults with Dementia in Alberta, Canada; A retrospective cohort analysis
DownloadSpring 2019
In Canada, one in five adults over the age of 80 have dementia. Dementia negatively impacts other chronic conditions and is associated with a higher risk of death, frailty and higher health-care costs. Health care transitions are major events; the abrupt nature of transitions, are confusing and...
-
Looking beyond the standard genome-wide association study: Biologically-motivated methodological approaches to discover novel genetic variants associated with complex human traits and disease
DownloadFall 2018
The standard approach for testing associations between common single nucleotide genetic variants (referred to as single nucleotide polymorphisms or SNPs) and disease entails testing disease associations for each SNP in the genome individually. This “hypothesis-free” approach has identified...
-
Management of Latent Tuberculosis Infection Among an Inner-city Population with Psychosocial Barriers to Treatment Adherence
DownloadFall 2020
BACKGROUND: In Canada, preventive therapy for LTBI has meant long durations and frequent dosing. This contributes to poor adherence and completion rates. In response, a shortened treatment regimen, once weekly rifapentine plus isoniazid for 3 months (3HP), is now available, though there has been...
-
Spring 2023
Background: Hemodialysis (HD) is a life-sustaining treatment for people with end-stage renal disease(ESRD). ESRD patients could experience severe adverse events when the water used during their HD treatments is not of the quality needed for its safe operation. The role of water quality in HD...
-
Fall 2020
Cost-utility analysis (CUA) assesses the cost-effectiveness of health technologies by comparing their costs and health outcomes. The utility is incorporated in the health outcome measures of CUA, and the EQ-5D-5L is one of the most common instruments to estimate utility values. When utility...
-
Mapping Patient and Caregiver Involvement across the Orphan Drug Lifecycle and in Programs that Provide Access to Promising Therapies While Ensuring Prudent use of Scarce Health Care Resources
DownloadFall 2016
Patients with rare diseases face significant challenges in accessing orphan drugs in Canada because of the uncertainties that decision-makers face when deciding whether or not to provide coverage for a new drug. While all coverage decisions are made under uncertainty, this uncertainty is often...
-
Measuring What Matters: Exploring Measures of Métis Children's Social and Emotional Well-being Through Evidence Synthesis and Consensus Group Methods
DownloadFall 2023
The measurement tools selected for use in studies with Indigenous children have an undeniable impact on the validity and applicability of the findings presented, underscoring the need to take seriously calls for the development of self-determined measures that are rooted in the cultures,...
-
Fall 2016
Background: A pilot community-based antiretroviral therapy (CBART) program in western Uganda was previously shown to significantly improve quality of life outcomes among HIV patients in their first year of treatment, though certain psychosocial challenges and issues remained. What is not known...
-
Meeting WHO’s Conditions For Labor Augmentation: A Narrative Literature Review on South Asia and A linked Analysis Using DHS 2016 and SPA 2015 Surveys in Nepal
DownloadSpring 2022
Background: Labor augmentation using oxytocin is commonly used throughout the world, but certain precautions need to be taken, and certain conditions need to be met; otherwise, complications are possible for both mothers and babies. Method: We conducted a narrative literature review study to...