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Fall 2013
Breast cancer is the most common cancer among women in the developed world. The disease results from the combined effects of genetic, environmental, reproductive and lifestyle risk factors. Germline DNA variations identified thus far by linkage and genome-wide association studies (GWASs) account...
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The Role of Oncogenic Tyrosine Kinase NPM-ALK in Anaplastic Large Cell Lymphoma Pathobiology
DownloadFall 2012
Anaplastic lymphoma kinase expressing anaplastic large cell lymphoma (ALK+ALCL) is an aggressive type of T/null cell lymphoma that mainly affects children and young adults and represents up to 40% of non-Hodgkin’s lymphoma in children. These lymphomas are characterized by the abnormal chromosomal...