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- 2Coulombe, Marilyne G.
- 2Logus, J. Wayne (John Wayne), 1951-
- 1Abdualla, Radya Y
- 1Abofayed, Hiatem Abdullah
- 1Agrawal, Amogh
- 1Ahmed, Iqbal Hussein, 1953-
- 7Primary Biliary Cholangitis
- 6Inflammatory bowel disease
- 5Inflammatory Bowel Disease
- 4B cells
- 4Endothelial cells
Role of membrane-type 1 matrix metalloproteinase in hematopoietic stem/progenitor cell traffickingDownload
Hematopoietic stem/progenitor cells (HSPC) are routinely used for transplantation to restore hematopoietic function; however, the molecular mechanisms governing their trafficking are not completely understood. Soluble matrix metalloproteinase (MMP)-2 and MMP-9 have been shown to mediate HSPC...
Benefits and Challenges of Implementing an Electronic Medical Record System in an Urban Slum in KenyaDownload
This Thesis consists of two papers that explore the use of Electronic Medical Record (EMR) systems in resource-limited settings. The first paper (Chapter 2) comprises a State-of-the-Art review of the types of inquiry, settings, interventions and principal findings reported from studies of the...
Methodological issues in randomized trials of pediatric acute diarrhea: evaluating probiotics and the need for standardized definitions and valid outcome measuresDownload
BACKGROUND: In a 2006 WHO report, diarrheal diseases ranked second among conditions afflicting children. Pediatric acute diarrhea, although most often the result of a gastrointestinal infection, can also occur as a result of antibiotic exposure. This is often referred to as...
Referral, Appropriateness and Eligibility of Implantable Cardioverter Defibrillator Therapy in AlbertaDownload
Background: Sudden cardiac death (SCD) is responsible for 50% of all cardiovascular deaths and is primarily due to rapid, life-threatening heart rhythm abnormalities. Multiple large, randomized clinical trials have demonstrated that implantable cardioverter defibrillator (ICD) therapy reduces...
Serial Fecal Microbiota Transplant Plus Fidaxomicin in the Treatment of Severe or Fulminant Clostridioides Difficile InfectionDownload
BACKGROUND Severe and fulminant Clostridioides Difficile infection (CDI) is associated with high rates of mortality and morbidity. Current practice guidelines recommend high dose vancomycin with metronidazole for treatment. Emerging evidence suggests efficacy of sequential fecal microbiota...
Effects of eight weeks of aerobic exercise training versus usual care on peak oxygen consumption, muscle mass, distance walked in six minutes and health related quality of life in Child Pugh clas A and B patients with cirrhosisDownload
Patients with cirrhosis have reduced peak exercise oxygen uptake (peak VO2) that is associated with decreased survival. The effect of aerobic exercise training (AET) on peak VO2 has not been well studied in cirrhosis. The purpose of this investigation was to evaluate the safety and efficacy of...