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Skip to Search Results- 2Coulombe, Marilyne G.
- 2Kinnaird, Adam
- 2Srivastava, Nutan
- 1Abdualla, Radya Y
- 1Abofayed, Hiatem Abdullah
- 1Aburahess, Salah
- 8Primary Biliary Cholangitis
- 7Inflammatory Bowel Disease
- 7Inflammatory bowel disease
- 6Endothelial cells
- 5Acute myeloid leukemia
- 5Mitochondria
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Evaluating Novel Prognostic Markers and Preventative Therapies for Chronic Lung Allograft Dysfunction after Lung Transplantation
DownloadFall 2023
Introduction: Survival following lung transplantation remains limited by chronic lung allograft dysfunction (CLAD). Few therapeutic options have been shown to be effective in established CLAD thus early detection and prevention are key. Objective: We aimed to identify potential early prognostic...
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1996
Submitted to the Faculty of Graduate Studies and Research in partial fulfilment of the requirements for the degree of Master of Science, Department of Pediatrics.
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Cytoskeletal Remodeling and Exocytosis During Mast Cell Activation is Controlled by the RhoA GEF, GEF-H1
DownloadFall 2021
Mast cells are tissue-resident immune cells that play important roles in health and diseases. Mast cells release their granule contents under antigen-stimulation via the FcεRI signaling pathway. The process of regulated exocytosis in mast cells is known as degranulation which participates in...
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Fall 2021
Background Mycosis fungoides (MF) is the most common cutaneous T-cell lymphoma (CTCL). Early stage disease, limited to skin patches & plaques, is indolent. However, progression to tumour stage disease marks a significant drop in survival to less than 4 years. Treatments for advanced disease are...
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Spring 2021
Decision-making is required for daily living. Specific decision-making ability in the area of finances is complex, and determining an individual’s capacity requires an in-depth assessment. In the presence of communication disorders such as aphasia, such assessments can become challenging, and...
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Structure and proteolytic digestion of the intrinsically disordered C-terminal tail of cardiac troponin I
DownloadSpring 2019
Intrinsically disordered regions (IDRs) are protein sequences that do not acquire a fixed 3-D configuration under physiologic conditions. Their solvent-exposed nature makes them susceptible to post-translational modifications like proteolysis, which makes them vital for cellular regulation....