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- 2Coulombe, Marilyne G.
- 2Logus, J. Wayne (John Wayne), 1951-
- 1Abdualla, Radya Y
- 1Abofayed, Hiatem Abdullah
- 1Aburahess, Salah
- 1Agrawal, Amogh
- 8Primary Biliary Cholangitis
- 7Inflammatory bowel disease
- 6Inflammatory Bowel Disease
- 5Endothelial cells
- 4B cells
- 4Crohn's disease
Neutrophils are highly abundant innate immune cells that are important in immediate responses to injury and infection, and secrete the proinflammatory cytokine tumor necrosis factor (TNF). Inflammatory cytokines have many potent effects and their excess or deficiency may have many clinical...
The Effect of Therapeutic Hypothermia on Neurological Outcomes Following Resuscitation from Cardiac ArrestDownload
Therapeutic Hypothermia (TH) is a relatively new therapy used to treat those resuscitated from cardiac arrest. The purpose of the therapy is to attenuate any neurological damage resulting from the arrest, thereby increasing survival and improving subsequent quality of life. The current evidence...
Epidemiological studies correlate vitamin D deficiency with asthma severity. Calcitriol modulates receptor and cytokine expression from various leukocytes in an anti-inflammatory manner. Despite eosinophil activity during mucosal inflammation, knowledge on the direct effect of calcitriol on this...
Proteinase-activated receptor-2 (PAR-2), a pro-inflammatory G-coupled receptor, is activated by exogenous or endogenous serine proteinases. PAR-2 is involved in the pathogenesis of inflammatory diseases including asthma. PAR-2 activation on airway epithelial cells (AECs) results in the release of...
ENDOTHELIAL CELL HETEROGENEITY: A CORRELATION WITH THE VON WILLEBRAND FACTOR EXPRESSION IN DISTINCT ORGANSDownload
Endothelial cells (EC) of different organs exhibit heterogeneity in structure, function and gene expression pattern. This also extends to the pattern in which the highly endothelial-specific gene, von Willebrand Factor (VWF) is expressed. VWF is a multimeric adhesive, pro-coagulant glycoprotein...
Maximizing the possibility of effectively treating cancer requires timely assessment of its aggressiveness and susceptibility to drug intervention. During cancer surgery, the “fast biopsy” is a commonly employed technique to assess a tumor’s invasiveness and guide surgery. Unfortunately, it is...
Pulmonary tuberculosis (TB) is a communicable disease that has an airborne route of transmission. It is a disease of poverty that exists in every country of the world. Within high-income, low TB burden settings, the disease increasingly affects vulnerable and underserved population groups who are...
Heart failure (HF) is a progressive and complex syndrome with poor prognosis, characterized by a wide array of cardiac structural and functional abnormalities. Patients are typically categorized according to left ventricular ejection fraction (LVEF), with reduced ejection fraction defined as...