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- 2Coulombe, Marilyne G.
- 2Logus, J. Wayne (John Wayne), 1951-
- 1Abdualla, Radya Y
- 1Abofayed, Hiatem Abdullah
- 1Agrawal, Amogh
- 1Ahmed, Iqbal Hussein, 1953-
- 7Primary Biliary Cholangitis
- 6Inflammatory bowel disease
- 5Inflammatory Bowel Disease
- 4B cells
- 4Endothelial cells
BackgroundThe assessment of acute pain due to trauma (APT) in adults is pivotal to clinical decision-making for optimal pain management. Clinicians are expected to employ validated measurement tools, such as the Numerical Rating Scale (NRS), to examine the complex and unique phenomenon of pain of...
Transmission of Tuberculosis from Patients with Typical Versus Atypical Chest Radiographs: Implications for Automated SystemsDownload
Automated detection of “typical” pulmonary tuberculosis (PTB) on chest radiograph (CXR) is warranted if it can be shown that patients with “typical” (vs “atypical”) CXRs are responsible for most public health consequences. Patient demographics and mycobacteriology of all adults (age >14 years)...
Understanding the Context of Pharmacy Practice Change: Gaining insight into the professional culture of pharmacy and pharmacists’ personalityDownload
Background: Pharmacists around the world are being asked to adopt, and integrate, an increasing number of clinical services into their practices. Evidence for the efficacy of pharmacists’ interventions in patient care also continues to grow. Traditional approaches to understanding practice change...
Thrombotic microangiopathies are group of diseases that refer to clinical and pathological syndromes where endothelial injury results in the manifestations of capillary thrombosis, microangiopathic hemolytic anemia, schistocytosis, and can lead to renal failure. In this thesis we aimed to study...
Renal cell carcinoma comprises approximately 2-3% of all malignancies, with the majority, approximately 70%, being clear cell renal cell carcinoma (ccRCC). ccRCC features many cancer hallmarks such as suppressed mitochondrial glucose oxidation, apoptosis-resistance, angiogenesis, immune evasion,...
Introduction: Acute blood pressure (BP) reduction is among the few treatments options available in the acute management of intracerebral hemorrhage (ICH). Recent observational studies have demonstrated the presence of lesions suggestive of ischemia on diffusion-weighted sequences (DWI) on MRI. We...
Primary Biliary Cholangitis (PBC) is a chronic liver disease characterized by the immune-mediated destruction of intra-hepatic bile ducts. The autoimmune nature of PBC involves humoral and cell-mediated responses that target endogenous mitochondrial proteins. It is thought that the breakdown of...
German Cockroach Extract Proteolytic Activity Down-regulates Interleukin-13 Dependent Eotaxin-3 (CCL26) Expression in Airway Epithelial CellsDownload
Introduction:Allergy to inhaled allergens is an important factor to develop airway inflammation. The airway epithelium is the main barrier between the host and inhaled allergens, and its activation by allergens is a key step towards the activation of innate and adaptive immunity. German cockroach...
Inflammatory bowel diseases (IBD) are a group of chronic inflammatory conditions including ulcerative colitis (UC) and Crohn’s disease (CD) induced by an interaction between genetic susceptibility, environmental factors, dysbiosis of gut microbiota and an abnormal mucosal immune response....