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- 138Department of Oncology
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- 12Department of Laboratory Medicine and Pathology
- 11Department of Biomedical Engineering
- 11Department of Medical Genetics
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Anti-cancer effects of n-3 long-chain polyunsaturated fatty acids (LCPUFA) on ovarian cancer growth in vitro and in vivo
DownloadFall 2019
Objectives: Many ovarian cancer (OC) patients relapse with chemo-resistant disease, necessitating improved therapeutic approaches. Recent studies have determined that long chain polyunsaturated fatty acids (LCPUFA) may affect cancer cell growth and metastatic potential; however, few studies have...
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Automatic Optimization of Treatment Dosimetry to Improve Visual Outcomes in Episcleral Plaque Brachytherapy
DownloadFall 2019
Ocular plaque brachytherapy is an effective treatment option for medium-sized ocular melanomas, showing equivalent survival relative to enucleation, while providing added benefits of eye preservation and possible vision retention. Currently the treatment planning system for plaque brachytherapy,...
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Binding, internalization, and transgene expression of an adenoviral vector retargeted to HER3/4
DownloadFall 2013
Adenoviruses (Ads) have been well studied for use in cancer gene therapy. However, low levels of the primary receptor, coxsackie-adenovirus receptor (CAR), in tumor cells has been shown to be a factor in low transgene expression. To increase Ad infection of breast cancer cells we constructed a...