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Skip to Search Results- 33Mass-spectrometry
- 24Chemistry
- 23Organic compounds. Synthesis.
- 22Metabolomics
- 21Capillary electrophoresis.
- 21Catalysis
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Fall 2019
Carboxylic acids are a ubiquitous class of molecules in the field of organic chemistry and represent versatile building blocks in synthetic chemistry. Methods that enable the formation of new carbon–carbon or carbon–heteroatom bonds from carboxylic acids via the extrusion of carbon dioxide can...
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Spring 2013
Fluorescent protein (FP) technology is now an indispensible tool of biomedical research. Nevertheless, only a few members of the hundreds of existing FPs are generally regarded as the preferred options for most imaging applications. Accordingly, new FPs with ever-improved properties are in demand...
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Fall 2013
The discovery of green fluorescent protein (GFP) from the Aequorea victoria Jellyfish followed by the extensive efforts of protein engineers to produce other fluorescent proteins (FPs) spanning the visible color spectrum made fluorescent proteins indispensable biochemical tools in the scientific...
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Development of New Late-Stage Labeling Methods with Labeled Carbon for Stabilized Carboxylic Acids and α-Amino Acids
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Isotope labeling of small molecules is a crucial tool for drug discovery and understanding biochemical processes. Expanding the toolbox of a radiochemist with methods that allow late-stage labeling is therefore important. Of the methods that have been developed, the use of isotopically labeled...
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Fall 2013
This dissertation describes the use of a novel Pt deposition to prepare nickel- and carbon-supported platinum catalysts. The deposition is referred to herein as the platinum counter electrode deposition. The source of platinum is the sacrificial dissolution of a blacked platinum counter electrode...
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Fall 2023
Three new Re(I) photocatalysts were prepared by synthesizing imidazole and imidazolium dyes based on carbazolyl dicyanobenzene derivatives and physically linking them to a Re metal centre for the photochemical reduction of CO2. The imidazolium dyes were of interest because they are precursors to...
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Fall 2014
The discovery and subsequent applications of fluorescent proteins (FPs) launched a new era for live cell fluorescence imaging. The design and developments of FP-based indicators have further solidified the versatility of FPs and rendered them as indispensable tools in life science research now...
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Development of Rh-Catalyzed Chemoselective Z-Olefin Synthesis and Ir- and Pd-Catalyzed Decarboxylative Enantioselective Benzylation
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Transition metal-catalyzed bond-forming reactions are powerful strategies in modern organic synthesis, which enable various functional group transformations and cross-coupling processes in a highly chemo-, regio- and enantioselective manner. Selectivity can be achieved through the appropriate...