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Skip to Search Results- 2Li, Leo
- 2Nizio, Katie D
- 1Abdel Latif Ibraheem, Ahmed Abdel Mohsen
- 1Abdelfattah, Ahmed
- 1Abel, Robin Jacob
- 1Abou-Ghanem, Maya
- 33Mass-spectrometry
- 23Organic compounds. Synthesis.
- 21Capillary electrophoresis.
- 21Catalysis
- 19Metabolomics
- 18Chemical reactions.
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Spring 2018
My Ph.D. research involved the generation of stimuli responsive poly(N-isopropylacrylamide) (pNIPAm)-based microgels and the modification of their chemistry to generate a series of pH responsive microgel-based optical devices (etalons). The pH responsivity of the synthesized microgels was used...
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Fall 2014
An organoarsenic compound, 3-nitro-4-hydroxyphenyl arsenic acid (also known as Roxarsone), has been used as a feed additive. Roxarsone was approved by the Food and Drug Administration (FDA) to control diseases in poultry, and to improve weight gain, feed efficiency, and meat pigmentation....
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Development of Blood Metabolomics for Biomarker Discovery Using Chemical Isotope Labeling and Liquid Chromatography-Mass Spectrometry
DownloadSpring 2018
Blood-metabolite-based biomarkers are useful for the early-stage diagnosis, accurate prognostic prediction and personalized treatment of various diseases. Blood contains a massive number of metabolites that can potentially become biomarkers, but the metabolome coverage of current analytical...
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Fall 2014
The five-membered carbocycle is a structural motif found in a plethora of natural products and bioactive compounds. The Nazarov reaction has emerged as an effective method to synthesize cyclopentenones and acts as a tool for adding structural complexity to molecular frameworks. This dissertation...
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Development and Application of Isotope Labeling Method and Data Processing Program for Liquid Chromatography Mass Spectrometry Based Metabolome Profiling
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The objective of this thesis focuses on establishing a software tool (IsoMS) used in the quantification and qualification of metabolites in complex biological samples, developing robust methods to extract metabolites from different plant samples, and applying a differential 13C-/12C-isotope...