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- 2Li, Leo
- 2Nizio, Katie D
- 1Abdel Latif Ibraheem, Ahmed Abdel Mohsen
- 1Abdelfattah, Ahmed
- 1Abel, Robin Jacob
- 1Abou-Ghanem, Maya
- 23Organic compounds. Synthesis.
- 21Capillary electrophoresis.
- 18Chemical reactions.
Peptides have a host of beneficial physiological effects and are often considered for therapeutic application to treat disease. However, poor bioavailabilities, problems with administration, sensitivity to environmental factors, and susceptibility to proteases limit them. The work presented in...
α-Synuclein is a protein that has been found as fibrillar aggregates in Lewy bodies in the brain of Parkinson’s disease patients. Though the cause of the Parkinson’s disease is unknown, previous research suggest that there is a close association between the disease and the toxicity of the...
Metabolite Identification and Quantification in Biofluids Using Liquid Chromatography Mass SpectrometryDownload
Metabolomics, one of the branches of systems biology, is the comprehensive measurement of all the endogenous metabolites in a biological system. It can be applied in the areas of biomarker discovery and diagnosis of critical diseases and disorders, and can significantly increase our understanding...
This thesis discusses the fate of individual enantiomers and isomers of organohalogen compounds (OHCs) in the environment and the development of analytical methods to facilitate such determinations. A novel proof of principle anion attachment atmospheric pressure photoionization (AA-APPI)...