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- 24Chemistry
- 23Organic compounds. Synthesis.
- 22Metabolomics
- 21Capillary electrophoresis.
- 21Catalysis
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The Design, Synthesis and Evaluation of Multivalent Heterobifunctional Ligands Specific for Shiga Toxin 1 and Shiga Toxin 2
DownloadSpring 2014
Hemolytic uremic syndrome (HUS) is a potential life-threatening condition caused by infection with Shiga toxin-producing Escherichia coli O157:H7. There are two major types of Shiga toxins, namely, Shiga toxin 1 (Stx1) and Shiga toxin 2 (Stx2), of which, Stx2 is clinically most closely associated...
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Fall 2019
Nowadays, rechargeable batteries play an ever more important role in our society as an energy storage medium for a wide range of applications from tiny electronic devices to grid-level energy storage. Among the different types of batteries, lithium-ion batteries (LIBs) have achieved significant...
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Spring 2010
McKnight-Whitford, Anthony Nicholai
Arsenic is a widespread environmental contaminant whose toxicity depends on its valence and its chemical form. Arsenic species have been typically determined using high pressure liquid chromatography coupled to inductively coupled plasma mass spectrometry (HPLC-ICPMS), however ICPMS cannot...
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Directed Evolution Approaches for Improved Genetically Encoded Fluorescent Calcium Ion and Voltage Indicators
DownloadFall 2014
Fluorescent proteins (FP) have revolutionized our imaging technologies and facilitated visualization of biochemical and physiological processes occurring in complex biological systems, which has opened up a new and unprecedented era in cell biology. Although FPs mainly serve as passive...
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Spring 2017
The work in this thesis describes advancements made towards developing main group catalysts and designing new ligands. N-Heterocyclic imine (NHI) ligands were used to support novel boron, silicon and germanium complexes. The new boron compounds demonstrated the ability to dehydrogenate...
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Fall 2020
The ability to amplify nucleic acid biomarkers at room temperature has remained elusive despite the great need of diagnostics suitable for the point of care. This thesis explores the probability of making lesion-induced DNA amplification (LIDA) an equipment-free platform that can work at room...