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Skip to Search Results- 33Mass-spectrometry
- 29Chemistry
- 23Organic compounds. Synthesis.
- 22Catalysis
- 22Metabolomics
- 21Capillary electrophoresis.
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Syntheses of Probes for the Elucidation of Biosynthetic Pathways and Interactions of Natural Products
DownloadFall 2018
A new platform for the semi-synthetic preparation of a known nanomolar inhibitor of the Plasmodium falciparum lysyl-tRNA synthetase, cladosporin, from Cladosporium cladosporioides and its analogues was developed. Our work has shown that it is produced biosynthetically by a highly reducing (HR)...
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A fluorescent protein exchange strategy for detecting protein-protein interactions and discovering proteinaceous inhibitors in Escherichia coli
DownloadFall 2015
Enterina, Jhon Ralph De La Peña
Green fluorescent protein (GFP), along with other GFP-like proteins, is one of the fundamental tools that are enabling the exciting current era of biological studies. The utility of GFP-like proteins as genetically encoded markers and sensors has provided us with powerful tools for tracking...
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Quantum Chemical Investigations of Structural and Photophysical Properties of Emissive RNA Nucleobase Analogues
DownloadFall 2017
The photostability of nucleic acid constituents is crucial in maintaining the integrity of our genetic code. This is achieved by the essential mechanism of ultrafast radiationless decay of the singlet excited state to the electronic ground state of nucleobases. While this mechanism provides...